The FAB Study – Mothers With a History of Depression

STUDY BASICS

Are you the birth mother of an 11-14 year old child? Have you experienced depression? If so, you and your child may be able to participate in a research study about how adolescents and their mothers respond to each other. Participation involves 3 in-person visits. You and your child will complete interviews, questionnaires, interactive tasks and activities, and a brain scan. Compensation provided.

STUDY PURPOSE

Depression is a serious and common illness. Symptoms of depression include feeling sad or hopeless, feeling tired or not having energy, changes in appetite or activity, and thoughts of death or suicide. The purpose of this study is to help researchers better understand how depressed mothers and their children respond to each other. Researchers will study mothers with and without depression and hope their findings will lead to better ways to prevent depression in children with a family history of mood disorders.

COULD THIS STUDY BE RIGHT FOR YOU?

• Women ages 21-64
• Biological mother of an 11-14 year old child
• Mother has experienced depression
• Mother has no history of bipolar disorder or psychotic disorder
• Child has no history of psychiatric disorders

WHAT PARTICIPANTS CAN EXPECT

Participation involves:

• A phone interview with the study team to find out if you are eligible
• 2 in-person visits at the CARE Lab, located in the Loeffler Building in Oakland. Each visit will take approximately 2-3 hours. During Visit 1, you will complete interviews and questionnaires. During Visit 2, you will complete interactive tasks and activities.
• 1 in-person visit at the Magnetic Resonance Research Center at UPMC Presbyterian Hospital lasting approximately 2-2.5 hours. During this final visit, both you and your child will undergo fMRI scanning.
• Online follow-up questionnaires at 6 months and 12 months after initial visit Compensation is provided for both mother and child.