Immune Interactions in Severe Asthma – Healthy Volunteers

STUDY BASICS

Are you a relatively healthy adult between 30 and 65 years old? If so, you may be able to participate in a research study to learn more about differences in the lungs and blood of people with and without asthma. Compensation provided.

STUDY PURPOSE

Severe asthma is poorly understood and difficult to treat. Researchers think that people with severe asthma may have differences in their lungs and blood, when compared to people with milder forms of asthma or with no asthma. The purpose of this study is to learn more about differences in the lungs and blood of people with and without asthma, and to find out how these differences are related to health outcomes over time. Researchers hope their findings will lead to better treatments for people with asthma in the future.

COULD THIS STUDY BE RIGHT FOR YOU?

• Relatively healthy men and women ages 30-65
• Non-smoker (former smokers must be tobacco-free for at least one year)

WHAT PARTICIPANTS CAN EXPECT

Participation lasts about 1 year and includes 3 office visits and 1 telephone call. Participants will have a physical exam and medical history, breathing tests, blood draw, and provide a urine sample. Participants will also undergo a bronchoscopy, which is the passage of a thin, flexible tube through the nose or mouth and into the lungs.