STUDY BASICS
Are you fully vaccinated against COVID-19? You may be able to participate in a research study to help find out if receiving a COVID-19 vaccine booster shot improves your immune response to prevent infection longer, more effectively, and/or from more variants. Most visits will include a blood draw. Compensation provided.
STUDY PURPOSE
For many infectious diseases, an extra dose of vaccine (also called a “booster shot”) is needed after initial vaccination to ensure lasting protection against infection. Some research suggests that COVID-19 booster shots may be beneficial for people who have already been vaccinated for COVID-19, but these effects are not fully understood.
The purpose of this research study is to learn about the safety, side effects, and immune responses associated with COVID-19 booster shots. This study uses vaccines that have received emergency use authorization by the United States Food and Drug Administration (FDA) and vaccines that are still under investigation.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 18 and up
- Healthy (participants with stable pre-existing disease are eligible)
- Fully vaccinated against COVID-19
- Received the COVID-19 vaccination at least 12 weeks ago but no more than 20 weeks ago
- Have never been diagnosed with COVID-19
- Not currently pregnant or breastfeeding
WHAT PARTICIPANTS CAN EXPECT
Participants will attend 7 or 8 study visits, including an initial screening visit, one study vaccination visit (may be combined with initial screening visit), and 6 follow-up visits. Study clinic visits may include a physical exam, and all but one will include a blood draw.
IRB: SSU00150890A
- NIH/NIAID/DMID - 21-0012, A Phase 1/2 Study of Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) after Receipt of EUA Vaccines (Pro00053376)MEET THE RESEARCHER
Judy Martin
Judy Martin, MD is a Professor of Pediatrics in the Division of General Academic Pediatrics at the University of Pittsburgh School of Medicine. A graduate of the University of Pennsylvania and Mount Sinai Icahn School of Medicine, Dr. Martin’s research interests include vaccine research, Group A streptococcal infections, and rheumatic fever.