Sleep and Cognition Study – Men Ages 55-64

STUDY BASICS

Are you a man between the ages of 55 to 64? Do you have trouble staying asleep at night? If so, you may be able to take part in a research study to see how sleep affects thinking and brain function. Participation involves two overnight sleep studies, cognitive tests, and two MRI scans. Compensation is provided.

STUDY PURPOSE

The purpose of this study is to understand how sleep affects thinking and decision making and to find out if deeper sleep improves cognition and brain function. Researchers also want to identify which sleep habits are best for older adults.

COULD THIS STUDY BE RIGHT FOR YOU?

• Men ages 55 to 64
• Difficulty staying asleep at night
• Able to do MRI scans (no metal in body or claustrophobia)
• Have not had a stroke or traumatic brain injury
• Not currently taking psychiatric medication
• Not being treated for sleep apnea
• Do not abuse drugs or alcohol

WHAT PARTICIPANTS CAN EXPECT

Study participation typically lasts 17 days and includes a phone screening and 3 visits. The first visit is a baseline screening visit with questionnaires, a clinical interview, and a medical exam with a study physician. Participants will then receive a sleep diary to fill out and an activity monitor to wear on their wrist for the duration of the study. Eligible participants will be invited to sleep in the lab for two separate overnight sleep studies. During each overnight visit, participants will be asked to perform cognitive tasks and complete a 15 minute MRI scan. Some participants will also be asked to follow a specific sleep schedule each night for one week between each sleep study.