The Microbiome, Stress, and Reward Study (MSR) – Parent with a History of Depression

STUDY BASICS

Are you the biological parent of a child 9-15 years old? Do you have a history of depression? If so, you and your child may be able to participate in a study to help better understand the relationship between the microbiome and depression. Compensation provided.

STUDY PURPOSE

Children who have a parent with a history depression are at an increased risk of developing it themselves. Recent research has found that the microbiome—the community of bacteria and microscopic organisms that live inside our bodies—may also play a role in the development of depression and other conditions. The purpose of this study is to help researchers better understand how the amount and types of gut bacteria relate to stress and reward responses in adolescents who have a biological parent with a history of depression. Researchers hope their findings will lead to better treatments for childhood depression in the future.

COULD THIS STUDY BE RIGHT FOR YOU?

• Biological parent of a child ages 9-15
• Parent has a history of depression

WHAT PARTICIPANTS CAN EXPECT

Participation involves up to 2 visits and involves the following:

• A clinical interview with you and your child
• Completion of questionnaires
• Child will undergo a painless, non-invasive EEG test that measures brain activity while they complete computer tasks and a stress test (public speaking and math tasks)
• Mailing a stool sample from your child to the study team. The study team will provide everything you need to collect the stool sample