Immune Interactions in Severe Asthma

STUDY BASICS

Are you between the ages of 18 and 65 and have you been diagnosed with mild to severe asthma? If so, you may be able to participate in a research study to help understand differences in the lungs and blood of people with asthma compared to healthy individuals. Compensation provided.

STUDY PURPOSE

Severe asthma, which affects approximately 5%-10% of asthmatics, is poorly understood and difficult to treat. Researchers think that people with severe asthma may have differences in their lungs and blood, when compared to people with milder forms of asthma or no asthma. The purpose of this study is to look at these differences and find out if how they are related to outcomes over one year.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 18-65
• Diagnosed with asthma (mild to severe)
• Non-smoker or tobacco-free for at least one year

WHAT PARTICIPANTS CAN EXPECT

Participation lasts about 1 year and includes 3-6 office visits and 1 telephone call. Participants will have a physical exam and medical history, breathing tests, blood draw, and provide a urine sample. Participants will also undergo a bronchoscopy, which is the passage of a thin, flexible tube through the nose or mouth and into the lungs.