The MINMON Study

STUDY BASICS

Do you have hepatitis C and have never before received treatment? If so, you may be able to participate in a research study to help find out if a simpler monitoring approach is safe and effective for people undergoing treatment for hepatitis C. Participants may or may not be diagnosed with HIV. Hepatitis C treatment will be provided to participants at no cost. Compensation provided.

STUDY PURPOSE

Hepatitis C is a disease caused by a virus that infects the liver. Over time, hepatitis C can lead to cirrhosis, liver cancer, and liver failure. New medications can cure most people with hepatitis C, but these treatments typically involve frequent clinic visits, blood tests, and prescription refills. For some people, this schedule can be difficult to follow. The purpose of this study is to find out if having fewer visits and tests is a safe and effective approach for people with hepatitis C undergoing treatment with an FDA-approved medication called sofosbuvir/velpatasvir (also known by brand name Epclusa®). Researchers hope that participants will be cured of hepatitis C and hope their findings will make it easier for people to receive treatment for hepatitis C in the future.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 18 and up
• Diagnosed with hepatitis C
• Have never been treated for hepatitis C with any medications
• Willing to take medication to treat your hepatitis C infection
• May or may not be living with HIV infection
• Agree to use contraception/birth control methods during the study period
• Not currently pregnant or breastfeeding
• Not infected with Hepatitis B

WHAT PARTICIPANTS CAN EXPECT

This study involves an initial screening period of up to 35 days to be sure you are eligible to participate in this study. If eligible after screening, participants will take the medication sofosbuvir/velpatasvir (Epclusa®) by mouth once a day for three months. Participants will have in person visits about 5 times, and will also be contacted by phone, email, and/or text at times during the study. During your study visits, participants will receive medication refills and have blood tests.