Brain, Emotion, & Sleep in Teens: The BEST Study – Parents with Bipolar Disorder

STUDY BASICS

Are you the biological parent of a teen aged 13-19 who is enrolled in high school and NOT diagnosed with bipolar disorder? Have you or your teen’s sibling been diagnosed with bipolar disorder? If so, you and your teen who does not have bipolar disorder may be able to participate in a study to help researchers learn more about how sleep impacts teenagers' moods. Compensation provided.

STUDY PURPOSE

Sleep problems are common in teens and can have a negative impact on their emotional well-being. The purpose of this study is to examine how sleep patterns in teenagers affect brain systems related to mood. Researchers also want to find out if improving sleep can change brain function and mood.

COULD THIS STUDY BE RIGHT FOR YOU?

• Biological parent of a teenager ages 13-19 years old who has not been diagnosed with bipolar disorder
• Parent or sibling of teen is diagnosed with bipolar disorder
• Teen without bipolar disorder willing to participate in this study with parent
• Teen currently enrolled in high school (grades 9-12)
• Teen willing and able to undergo MRI scanning

WHAT PARTICIPANTS CAN EXPECT

Study participation involves at least 2 visits. During the first visit, both parent and teen will be asked to complete questionnaires. The teen will also be asked to answer questions about his/her daily sleep and to wear an activity watch for 2 weeks following the first visit. During the second visit, both parent and teen will be asked to complete questionnaires. The teen will also be asked to have an MRI (magnetic resonance imaging) brain scan for 1 hour while completing computer tasks. If asked to participate in the optional study, the teen will be asked to keep a regular sleep schedule (go to bed and wake up at the same time every day) for 2 weeks, answer questions about sleep patterns, and wear an activity watch. Both parent and teen will also return for an additional visit that includes an MRI scan and questionnaires.