Acute Sinusitis Study

STUDY BASICS

Does your child have a cold that does not seem to go away or has suddenly gotten worse? If so, your child may have sinusitis (sinus infection) and may be able to participate in a research study. Compensation provided.

STUDY PURPOSE

The purpose of this research study is to find out whether it is better to treat a sinus infection with an antibiotic right away, or if it is better to wait a few days to see if symptoms improve on their own.

COULD THIS STUDY BE RIGHT FOR YOUR CHILD?

• Between the ages of 2-12
• Has a cold that does not seem to go away or has suddenly gotten worse

WHAT PARTICIPANTS CAN EXPECT

This study involves 2-3 visits over several weeks. Parents will be asked to report their child’s symptoms in an electronic diary each day. Some children who participate in this study will be given an antibiotic and some will be given a placebo. The placebo looks and tastes just like the antibiotic but does not contain the antibiotic. Your child will be assigned by chance, like the flip of a coin, to receive either antibiotic or placebo. Participants will be seen at various Children’s Hospital of Pittsburgh (CHP) and Children’s Community Pediatrics (CCP) locations.