Hero image with Pittsburgh background pittplusme.org/study/1376

Pitt+Me RAD-SD Study – Age 18


STUDY BASICS

Are you 18 years of age and currently depressed? If so, you may be able to participate in a research study to help find out if an intervention that targets the sleep-wake cycle is a safe and effective approach for improving depression symptoms. The intervention used in this study is not invasive and does not involve medications. Compensation provided.


STUDY PURPOSE
Many young adults experience depression, a serious mood disorder that causes feelings of intense sadness, lowered energy, lack of interest in activities, academic problems, and withdrawal from others. Standard treatments for depression include antidepressant medications and counseling, but these may take weeks or months to work, or may not work at all. Some studies have shown that blocking a part of sleep that is abnormal in depression can rapidly improve depression symptoms, but this effect is not fully understood. The purpose of this study is to find out if an intervention that targets the sleep-wake cycle is a safe and effective approach for improving depression symptoms in young adults, and to better understand how sleep affects brain systems related to mood. The intervention used in this study is not invasive, does not involve medications, and does not shorten the duration of sleep. Researchers hope their findings will lead to better treatments for young adults with depression in the future.
COULD THIS STUDY BE RIGHT FOR YOU?
  • Age 18
  • Currently depressed
  • No history of bipolar disorder or schizophrenia
  • No serious medical or neurological conditions
  • Not taking any psychiatric medications other than selective serotonin reuptake inhibitors (SSRIs) such as Zoloft, Prozac, Paxil, Lexapro, or Celexa
  • Willing and able to undergo MRI scanning (no non-removable metal in the body, and not claustrophobic)

WHAT PARTICIPANTS CAN EXPECT
Participation involves completing an initial assessment to find out if you are eligible to participate in this study. During this visit, you will complete interviews and questionnaires about sleep, mood, and medical history. If eligible after this visit, you will be invited to participate in 3 consecutive overnight visits at the UPMC Sleep and Behavioral Neuroscience Center. These visits typically occur Thursday, Friday, and Saturday nights from about 8pm to 11am the next morning. During these visits, you will have your sleep monitored and auditory tones will be played to suppress certain parts of your sleep. You will also have 2 MRI scans and will complete questionnaires. In the month after the final overnight visit, you will be asked to compete a brief set of forms about mood and sleep at home, once a week for 4 weeks. These forms can be completed on paper or online.
IRB:
  STUDY19040072B - Rapid Antidpressant Effects of Selective Slow-Wave Sleep Deprivation for Depressed Youth


Age Range
AGE:   18

Duration VISITS:  4 visits

Location LOCATION: 
Western Psychiatric Institute and Clinic (WPIC)
Compensation COMPENSATION: 

Up to $230

Phone Number PHONE NUMBER:
1-866-438-8230
I'M INTERESTED
SHARE STUDY
Printer Printer   Email A FriendEmail A Friend   ShareShare   TweetTweet   Linked-InLinked-In
Search Icon pittplusme.org/study/1376
OR
Phone Number PHONE NUMBER:
1-866-438-8230

MEET THE RESEARCHER


Adriane Soehner

Adriane M. Soehner, PhD, is an Assistant Professor of Psychiatry at the University of Pittsburgh. A graduate of the University of California, Berkeley, Dr. Soehner’s research investigates the role of sleep in brain development and psychiatric illness.




PittPlusMe.org 1-866-438-8230 PittPlusMe@pitt.edu
@PittPlusMe share tweet

Pitt+Me

This website is maintained by the Clinical and Translational Science Institute.
© Copyright 2018, University of Pittsburgh. All rights reserved.