Hidradenitis Suppurativa (HS) Study

STUDY BASICS

Do you have Hidradenitis Suppurativa (HS)? You may be eligible for a research study assessing an oral investigational medicine for HS to see if it can reduce the number of skin bumps in those with moderate-to-severe disease. Study participation will last about 6 months and include up to 14 visits. Compensation is provided.

STUDY PURPOSE

Hidradenitis  Suppurativa  (HS) is a chronic (long-lasting) disease that causes painful lumps under the skin. These lumps are usually on parts of the body where skin touches skin (including the armpits, inner thighs, and/or the groin area).  The main goals of this study are to see how the investigational medication compares to placebo on its ability to reduce the number of HS-related skin lumps (i.e., abscesses and inflamed nodules) in adults with moderate-to-severe Hidradenitis Suppurativa, as well as to assess its safety and its effect on pain levels. 

COULD THIS STUDY BE RIGHT FOR YOU?

• You are 18 to 70 years of age 
• You have had signs/symptoms of Hidradenitis Suppurativa for a minimum of one year 
• You have had an inadequate response to at least a 1-month treatment with an oral antibiotic taken for your HS
   

WHAT PARTICIPANTS CAN EXPECT

• Your involvement will last approximately 24 weeks, including 4 weeks after the treatment period ends, during which time we’ll follow up with you about your health
• Participants will be randomly assigned to receive one of the following, with a 66% chance to receive active treatment vs 33% chance to get placebo:
  • Study medication
  • Placebo (inactive medication)
• You will receive an e-diary to record things like your pain and itch levels each day, your daily study drug intake, any pain medicines used, as well as any disease flare-ups so the study team can monitor how you’re doing.
• Study doctors will closely monitor your health during and after the study