TOPMAS - Transcript/Omics for Precision Medicine in Asthma (Pediatric Arm)

STUDY BASICS

Are you the parent of a 6-17 year old? Do they experience mild to severe persistent asthma? You and your child may be able to participate in a research study to better manage asthma in patients with severe disease. Compensation is provided.

STUDY PURPOSE

The goals of this study are to identify biological characteristics, including genetic differences, that can help us to predict asthma exacerbations, and to better manage asthma in patients with severe disease. 

COULD THIS STUDY BE RIGHT FOR YOUR CHILD?

Eligible participants:

• Are children ages 6-17
• Have mild, moderate, or severe persistent asthma 

WHAT PARTICIPANTS CAN EXPECT

This study will include two groups of patients. Both groups will complete questionnaires, breathing tests, and nasal and blood samples. 

Group 1 will include patients with mild, moderate, or severe persistent asthma. The study will last approximately 1 year. There will be two in-person visits: at the start of the study and 6 months later; and three phone/virtual visits: at 3, 9, and 12 months after starting the study. 

Group 2 will include patients with severe asthma who are about to start asthma medications called biologics. The study will last approximately 6 months. There will be two in-person visits: at the start of the study and 6 months later; and one phone/virtual visit 3 months after starting biologic therapy. 

Each in-person visit may take up to 1.5-2 hours, and virtual/phone visits may take up to 30 minutes.