DD Study – Healthy Volunteers

STUDY BASICS

Are you 18-45 and right-handed? If so, you may be eligible to participate in a research study to help learn more about brain function in adults with and without bipolar disorder. Eligible participants have no history of any mental health disorder, such as depression. Study involves a clinical evaluation, questionnaire completion, and fMRI scanning. Compensation provided.

STUDY PURPOSE

Bipolar disorder, also sometimes known as manic-depressive disorder, is an illness that causes extreme mood changes from manic episodes of very high energy to extreme lows of depression. The purpose of this study is to help researchers better understand brain function in adults with and without bipolar disorder. Researchers hope their findings will lead to better ways to diagnose and treat bipolar disorder in the future.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 18-45
• Right-handed
• No history of any mental health disorders, such as depression
• No major physical medical problems, such as diabetes
• Not claustrophobic
• No permanent metal (like surgical pins) in your body
• Not pregnant
• Do not have any alcohol/substance use disorder and/or illicit substance use in the past 3 months

WHAT PARTICIPANTS CAN EXPECT

This study involves an initial 3-hour screening visit that includes interviews, questionnaires, tests of reading, memory, and vision, and questionnaires. Eligible participants will also have an fMRI scan visit that will take about 2 hours to complete. An fMRI scan is a type of imaging technique used to take pictures of your brain. fMRI scans are not invasive or painful and do not use radiation. Participants will also be asked to provide urine and saliva samples at this visit.