COZI Study

STUDY BASICS

Can’t sleep? COZI is a national research study to find out which insomnia treatment is best— behavioral therapy, medication, or both. If you are 18–80 years old and have regular internet access you may be eligible for COZI. We are particularly interested in adults who live in rural areas. Compensation provided.

STUDY PURPOSE

The purpose of the study is to understand how adults with insomnia respond to different treatments for insomnia. We are particularly interested in adults who live in rural areas because some insomnia treatments may not be as easy to access outside of large cities. 

COULD THIS STUDY BE RIGHT FOR YOU?

• 18 to 80 years old 
• have insomnia
• are willing to receive behavioral treatment, medication treatment, or a combination
• have regular access to the internet
• receiving care at one of the following UPMC practices
  • Bedford Internal Medicine (Bedford, PA)
  • Hermitage Community Medicine (Hermitage, PA)
  • Partners In Health (Irwin, PA)
  • Shenango Valley Family Medicine Center (Farrell, PA)
  • Steel City Internal Medicine (Ellwood City, PA)
  • Family & Lifestyle Medicine Partners (Hermitage, PA)

WHAT PARTICIPANTS CAN EXPECT

Your participation in the study lasts approximately 12 months and includes the following research procedures:

• Initial evaluation – Interview (30 min over the phone) and questionnaires (30 – 45 min online)
• Insomnia intervention – Randomly assigned (like the flip of a coin) to one of the 3 following treatments:
  • Internet Cognitive Behavioral Treatment for Insomnia (CBT-I) – self-guided, interactive, web-based program to manage sleep problems using behavioral changes and other exercises
  • Medication– Your provider will prescribe either trazodone or zolpidem for your insomnia. Zolpidem is a widely prescribed medication treatment for insomnia. Trazodone is a medication originally used to treat depression, but now commonly used to treat insomnia. In this study we are looking at its effectiveness for treating insomnia, using doses lower than those for the treatment of depression.
  • CBT-I plus Medication – combination of interventions listed above.
• Follow-up evaluations up to one-year post intervention – Questionnaires (30 – 45 min online)