ASPIRIN Study
STUDY BASICS
Are you pregnant? You may be eligible for a research study to compare two doses of aspirin to see if one is better at preventing hypertensive disorders of pregnancy and improving outcomes for mom & baby.
STUDY PURPOSE
The purpose of the ASPIRIN Study is to compare two doses of aspirin to see if one is better at preventing hypertensive disorders of pregnancy and improving outcomes for mom & baby.
COULD THIS STUDY BE RIGHT FOR YOU?
- Age 14 or older
- Under 17 weeks pregnant
- Planning to deliver your baby at UPMC Magee-Women's Hospital in Pittsburgh
WHAT PARTICIPANTS CAN EXPECT
You will:
- Be randomized (almost like rolling a dice) to 81mg or 162mg of aspirin (you and your provider will not know which dose you will be taking)
- Be provided with the aspirin medication and asked to take it for the duration of your pregnancy
- Complete up to 6 visits (virtual or in person) to gather information on any side effects
- Complete surveys approximately 4-6 weeks after birth.
The study team will:
- Work with your provider to let them know you are participating in this study.
- Gather information on you and your child throughout your pregnancy and after delivery.
IRB: SSU00264718
- The Ohio State University - Pro00079100, Comparative effectiveness of two aspirin doses for prevention of hypertensive disorders of pregnancy: ASPIRIN Trial (Pro00079100)MEET THE RESEARCHER

Hyagriv Simhan
Hyagriv Simhan, MD, MSCR, is professor at the University of Pittsburgh School of Medicine, and chief of the division of maternal-fetal medicine and medical director of obstetrical services at Magee-Womens Hospital of UPMC. His main area of research has been on preterm birth. Because of his efforts to improve patient safety and quality of care, Dr. Simhan has been awarded the Fine Award from the Pittsburgh Regional Health Initiative, and the Achievement Award for Health Care Quality Improvement/Patient Safety from the Hospital Association of Pennsylvania.