PREPARE-1 Study

STUDY BASICS

Are you having a cesarean delivery? You may be eligible for a research study to investigate the use of ketamine to improve pain management after cesarean delivery. Compensation is provided.

STUDY PURPOSE

Ketamine is a safe, effective non-opioid, FDA approved drug used to reduce pain and treat depression. Ketamine has been shown to lower the need for taking opioid medications. The purpose of this study is to determine tolerable doses of ketamine post-cesarean delivery. Our study will determine whether side effects are acceptable to new moms. This knowledge will help us identify alternatives to opioids to treat and manage post-cesarean pain and depression. 

COULD THIS STUDY BE RIGHT FOR YOU?

Eligible participants are:

• Adults 18 years and older 
• Planning a Cesarean Delivery 
• Expecting delivery between 37-42 weeks gestation
• Not breastfeeding your infant 

WHAT PARTICIPANTS CAN EXPECT

If you are eligible and interested in participating, you will complete a series of questionnaires prior to your surgery, receive an infusion of ketamine after your cesarean delivery, and complete weekly questionnaires about your mood and pain throughout the first 3 months postpartum. 

These questionnaires will assess mood, stress levels, pain, experiences breastfeeding and with your infant in general, as well as use of medications for pain management. These questionnaires will typically be administered electronically and require less than 25 minutes to complete.