Kaempferol Absorption and Pharmacokinetics Evaluation (K.A.P.E.)

STUDY BASICS

Researchers at the University of Pittsburgh are conducting a clinical research study to better understand how the natural compound Kaempferol (KMP) is absorbed and processed by the human body. Kaempferol is a plant-derived flavonoid found in foods such as kale, tea, and apples. This research will help determine how KMP behaves in the body. Compensation is provided.

STUDY PURPOSE

This study will look at how the body handles Kaempferol (KMP), a natural substance found in many fruits and vegetables such as apples, onions, kale, broccoli, and green tea. We want to learn how the body absorbs it, how long it stays in the body, and whether people in the United States respond to it in the same way as people in earlier studies done in Japan. KMP has already been shown to be safe, and this study will help us better understand any possible health effects.

COULD THIS STUDY BE RIGHT FOR YOU?

• Are 18 to 70 years old
• Are in generally good health
• Are not currently pregnant or breastfeeding
• Are not taking prescription medications that may interfere with supplement metabolism
• Are willing to provide blood and urine samples over an 8-day study period

WHAT PARTICIPANTS CAN EXPECT

If you qualify and choose to participate, you will:

• Attend clinic visits over 8 days
• Take a dietary supplement containing Kaempferol
• Provide blood and urine samples for analysis
• Complete short questionnaires about your health and experience

Total time commitment: approximately 10–12 hours across the 8-day period.  All study procedures will be performed by qualified clinical staff.