PRISM Study - Recent Suicidal Thoughts or Behaviors

STUDY BASICS

Have you had recent suicidal thoughts or behaviors? Are you 18-30 years old? If so, you may be able to participate in a research study to help learn more about brain activity in people with suicidal thoughts or behaviors. Compensation is provided.

STUDY PURPOSE

Suicide is the 10th leading cause of death in the United States. Although there are often warning signs that someone is thinking about suicide, it is difficult to predict who will go on to attempt or commit suicide. The purpose of this study is to help researchers learn more about brain activity in people with suicidal thoughts or behaviors by studying how they think about words related to positive and negative emotions. Researchers hope their findings will lead to better ways to assess and treat people who experience suicidal thoughts and behaviors.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 18-30
• In the past two weeks, have had suicidal thoughts or behaviors, or a suicide attempt
• Not currently taking any drugs, unless they were prescribed to you by your physician
• Willing and able to have an fMRI scan (right-handed, no non-removable metal in the body, not claustrophobic)
• Not pregnant

WHAT PARTICIPANTS CAN EXPECT

Participation in this study involves up to 5 visits over the course of 9 months. Some visits may be completed over the phone. Visit 1 involves an interview, computer-based tasks, and an fMRI scan. During visit 2, participants will have another interview and fMRI. Participants will also have 1 hour follow-up interviews (in-person or over the phone) at 6 and 9 months. Interviews will be audiotaped with your permission. All participants will be asked to give a urine sample before undergoing fMRI scanning to screen for drugs and alcohol, and for pregnancy in women. fMRI scans are not invasive and do not use radiation.