Many people take aspirin to lessen pain, lower a fever, or prevent a heart attack or stroke, but new research published in the Journal of Experimental Medicine reports that taking aspirin may also help treat patients with some types of head and neck squamous cell carcinoma (HNSCC)—cancers that affect the mouth, throat, voice box, nose, and sinus cavity. Researcher Matthew Hedberg, MD, PhD, and his team at the University of Pittsburgh found that regular use of aspirin improved outcomes for...

We all know that it is important to get a good night’s sleep, and this may be especially important for older women. New research from Jane Cauley, DrPH, of the University of Pittsburgh Graduate School of Public Health, published in the Journal of Bone and Mineral Research, found that women who slept poorly, or slept too much or too little, had an increased risk of falling and breaking a bone. Dr. Cauley and her team studied self-reported data from 157,306 postmenopausal women aged 50-79 and...

Could an over-the-counter supplement help people with inflammatory bowel disease (IBD), an umbrella term for conditions such as ulcerative colitis and Crohn’s disease that involve immune response and inflammation of the gastrointestinal tract? In findings published in the American Journal of Gastroenterology, University of Pittsburgh senior author David Binion, MD, and his team reported that low vitamin D levels—a vitamin that is available in foods, as a dietary supplement, and when ultraviolet...

The Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh is pleased to announce that the Pitt+Me® Registry—currently celebrating its 10 year anniversary!—enrolled its 200,000th participant in March 2019. This large and diverse group of adult and pediatric participants helps Pitt and UPMC researchers make groundbreaking discoveries, gives Western Pennsylvanians access to innovative research studies, and contributes to advancing exceptional medical care across the...

Children who grow up in poverty often have mental health and behavioral issues that extend into their adult lives, but research shows that there are ways to help prevent these negative effects. A study published in the journal Child Development by University of Pittsburgh researcher Jamie Hanson, PhD, and his team found that family-based interventions helped children emotionally combat the negative effects of poverty by strengthening connections between important parts of each child’s brain. ...

Could a person’s heart health provide clues about their dementia risk? Study findings from University of Pittsburgh doctoral student Chendi Cui, PhD, and her team published in the Journal of Alzheimer’s Disease, found that stiffness in the aorta—the body’s main artery—is associated with an increased risk of dementia. As part of the long-term Cardiovascular Health Study at Pitt, researchers measured aortic stiffness using a non-invasive test called pulse wave velocity (PWV) and assessed brain...

By the age of 60, almost one in three Americans experience fat pad atrophy of the foot—a breakdown of the shock-absorbing pad in the ball of the foot that can lead to foot pain, ulcers, and callus formation. A new study from University of Pittsburgh researcher Jeffrey Gusenoff, MD, shows that fat grafting, a minimally-invasive procedure in which a person’s own fat is removed from one area and injected into another, can provide long-lasting improvements in foot pain and function for patients...

Understanding cold-related injuries is important for parents at this time of year, according to Raymond D. Pitetti, MD, MPH, associate professor of pediatrics, University of Pittsburgh School of Medicine. There are two broad categories for cold injuries—freezing injuries like frostbite, and nonfreezing injuries like hypothermia. Kids are especially at risk for both types of cold injuries, in part because when they are having fun outside they just don’t know when to quit! Kids are also different...

For people experiencing the loss of a loved one, the holidays can be a painful time of year. Festive music, decorations, and holiday parties meant to bring comfort and joy can instead serve as painful reminders of the loss, and many bereaved individuals are faced with making new holiday rituals and traditions. University of Pittsburgh Department of Psychiatry researcher Sarah Stahl, PhD, whose work focuses on improving the mental and physical health of bereaved older adults, shares her tips for...

We hear a lot about the negative impacts of video games, but recent research suggests they may help emergency room physicians improve their skills. Medical errors are common, and the emergency room can be a particularly challenging setting for doctors to make an accurate diagnosis due to limited time and information available. Pitt researcher Deepika Mohan, MD, MPH, and her team set out to develop a video game solution that would help emergency room doctors make better decisions about care...

School suspension rates are high in some Allegheny County school districts, and a new report shows that African American students are suspended at much higher rates than their non-Black classmates, according to a report from University of Pittsburgh researchers James P. Huguley, EdD, and Ming-Te Wang, EdD. High suspension rates were found to be related to poor academic performance, lower graduation rates, and increased contact with justice officials­­—often referred to as the “school-to-prison...

“What is your idea to improve human performance?” That was the question posed to researchers at the 2018 Pitt Innovation Challenge (PInCh) contest, during which teams presented their innovative solutions for a range of health issues including asthma, cancer, catheter care, COPD (chronic obstructive pulmonary disease), fall prevention, foot surgery, medication dosing, sleep disorders, sports injuries, tremor, and others. Presenters competed for cash awards of $25,000 or $100,000, plus ongoing...

If you’re interested in participating in the All of Us Pennsylvania Research Program, we have great news! In addition to the Pittsburgh and Altoona sites, you can now schedule enrollment visits at new locations in the North Hills at UPMC Hampton, in the South Hills at St. Clair Commons in Bethel Park, and at UPMC Magee-Womens Hospital in Oakland. In addition, look for the All of Us PA pop-up clinics at various other locations around Pittsburgh and beyond. Part of a national study that aims to...

Your new profile picture on Facebook received a lot of likes and complimentary comments, but the one person who said she hated your shoes has really got you down. Sound familiar? While social media allows for increased connectivity and social interaction, a new study from the University of Pittsburgh reports that negative experiences on social media may have more impact than positive ones for young adults. Researchers at Pitt surveyed 1,179 West Virginia University students ages 18 to 30 to...

  Following a severe injury, uncontrolled blood loss often leads to life-threatening complications. But a new study from the University of Pittsburgh shows that two units of plasma—a yellowish liquid that helps blood clot—given during air transport to the hospital could increase the odds of survival by 10 percent for traumatically injured patients with severe bleeding, according to the results of a national clinical trial published in the New England Journal of Medicine. Researchers from nine...