About Kidney and Urinary System
While the digestive tract removes solid waste from the body, it’s the job of the kidneys and the urinary system to filter and pass liquid waste. The two kidneys continuously work to filter blood, removing waste products and excess fluids. This combined fluid waste, urine, gets passed to the bladder before being flushed out of the body. If the kidneys are overworked or weakened, serious issues can result. If the mineral levels in your blood are too high, painful kidney stones can develop. Other conditions, especially diabetes and high blood pressure, can cause disease by reducing the kidneys’ ability to filter. Studies in this field might also look at issues related to urination, from incontinence (the involuntary release of urine) to overactive bladder. Because of the waste products contained in urine, the urinary tract is also at risk for infections. By studying these and other urinary issues, Pitt researchers hope to provide relief to everyone.
Urinary Urge Incontinence Study
Do you experience a sudden, strong urge to urinate or “overactive bladder” that sometimes results in urine leakage? Do situations such as running water or approaching the front door trigger your urgency? Women aged 40 or older may be able to participate in a research study to help find out if two non-drug treatments can improve urinary incontinence. Compensation and travel expenses are provided.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
Are you a woman who experiences urine leakage with BOTH coughing, laughing, physical activity AND have a sudden, strong urge to urinate? Are you interested in treatment? You may be able to participate in a study to find out which treatment for mixed urinary incontinence should be offered first. Study participants will be randomized to receive BOTOX injections in the bladder or a urethral sling.
Brain and Bladder Study – Females Aged 18-45
Are you female and aged 18-45? Do you experience “overactive bladder” and urinary urge incontinence (a sudden, strong urge to urinate that results in urine leakage)? You may be able to take part in a research study to help better understand the relationship between the brain and the bladder. Compensation and transportation/parking provided.
Exploring the Brain-Bladder Connection
Are you a woman aged 60 or older who regularly experiences ‘urinary urgency’ (a sudden, strong need to urinate) or ‘overactive bladder’ with urine leakage? If so, you may be able to participate in a research study to help better understand the relationship between the brain and the bladder in women who have urgency urinary incontinence. Compensation provided.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Urea for Chronic Hyponatremia Study
Are you an adult who has chronic low blood sodium levels (also called hyponatremia)? You may be able to participate in a research study to find out if a dietary supplement called Urea is a safe and effective treatment for people who have chronic hyponatremia. Compensation and parking provided.
HOPE Buprenorphine Stigma Study
Do you have an active end-stage kidney disease diagnosis and have undergone in-center dialysis treatment within the past 3 months? You may be able to participate in a study to better understand chronic pain and opioid stigma in individuals with end-stage kidney disease on dialysis. Eligible participants will complete an audio-recorded interview that will last one hour. Compensation is provided.
Focal Segmental Glomerulosclerosis (FSGS) Study
Are you living with kidney disease caused by focal segmental glomerulosclerosis (FSGS)? Are you of African or Caribbean descent? If so, you may be able to participate in a study to see if you have a genetic mutation (a change in your DNA). This study involves a 30-minute visit where you will undergo a blood draw. Compensation is provided.