About Digestive System
From the moment the body takes a bite of food, the digestive system starts its work. The mouth, stomach, and intestines work together to break down food into more usable forms, aided by chemicals called enzymes that are produced and stored in the liver, pancreas, and gall bladder. Once nutrients have been extracted from food, the remaining waste is passed to the colon to be released. When working properly, the digestive system provides the body with fuel for energy and the materials needed for repairs and growth.
HM-TRIA-201 Study for NASH
Do you have nonalcoholic steatohepatitis (NASH)? You may be able to participate in a study to help test an investigational drug called HM15211 to see if it can safely be used to reduce liver inflammation in people with NASH. Eligible participants are 18-70 years old. This study involves about 21 visits over 15 months. Compensation provided.
Blood Test Study for Suspected Liver Disease
Have you been scheduled for a liver biopsy because your doctor suspects that you may have non-alcoholic fatty liver disease (NAFLD)? If so, you may be eligible to participate in a study to help evaluate a new blood test for liver disease. This study requires a one-time visit and blood draw. Compensation is provided.
The Voyage Study (VK2809-202)
Have you been diagnosed with non-alcoholic steatohepatitis (NASH)? If so, you may be able to participate in a research study to help find out if an investigational drug called VK2809 is safe and effective for the treatment of NASH. This study involves 16 in-person visits over up to 16 months. Compensation is provided for inconveniences incurred.
The NN9500-4656 Study
Do you want to address your liver health? Do you have non-alcoholic steatohepatitis (NASH)? You may be able to participate in a study that is evaluating three investigational drugs for their ability to treat NASH.
Do you have Primary Biliary Cholangitis (PBC)? You may be able to participate in a study to find out how safe and effective an investigational drug called elafibranor is for patients with PBC. The main part of the study lasts up to 2 years, but total participation can last up to 6 years. Compensation and reimbursement are provided.
DREAM Acute Pancreatitis Study
Are you 18-75 years old? Have you recently had an acute pancreatitis attack? You may be able to participate in a study to determine if acute pancreatitis increases your risk for diabetes. This study involves up to 9 visits over 3-5 years, and includes providing blood samples and undergoing tests to detect diabetes. Compensation is provided.
Brain Stimulation Study - Adults with Functional Dyspepsia and/or Irritable Bowel Syndrome
Have you been diagnosed with functional dyspepsia and/or irritable bowel syndrome? If so, you may be able to take part in a research study to help better understand how non-invasive brain stimulation affects communication between the brain and the body. Involves no more than 10 study sessions that can take 2-3 hours each. Compensation is provided.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Improving Pain Management and Opioid Safety for Patients with Cirrhosis
Have you been diagnosed with cirrhosis, and have you been living with chronic pain? You may be able to participate in a study that will evaluate the use of a health education program for patients with cirrhosis. Compensation is provided.
Are you 18-79 and diagnosed with nonalcoholic fatty liver disease (NAFLD)? You may be able to participate in a study to help find out why some people who have fatty liver disease develop more severe liver disease such as cirrhosis or liver cancer while others do not. Participation will last at least 5 years and will involve annual visits. Compensation is provided.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
Do you have severe itch associated with primary sclerosing cholangitis (PSC)? You may be able to participate in a research study to find out if an investigational medication called volixibat is a safe and effective treatment for itching associated with PSC and if it may improve markers associated with PSC disease progression. Compensation is provided.
Smartphone Training for Attention Regulation for IBS Study
Have you been diagnosed with IBS (irritable bowel syndrome)? You may be able to participate in a study to try to make life with IBS more comfortable. This study includes 3 in-person visits and involves completing a 14-day program on your smartphone at home where you will track your IBS symptoms. Compensation is provided.
Genetics of Inflammatory Bowel Disease – Healthy Volunteers
Are you a healthy, white individual between the ages of 18 and 35? If so, you may be eligible to help researchers understand the genetics of inflammatory bowel disease (IBD). Researchers hope to identify IBD-causing genes, which determine a person’s make-up and inherited traits. Involves one study visit, participants will be asked to give approximately 4 tbsp. of blood. Compensation provided.
Biliary Atresia Study
Are you age 18 or older with a diagnosis of biliary atresia? Have you had the Kasai procedure (surgery to improve bile flow)? If so, you may be able to participate in a research study to learn more about the long term health of patients who have had the Kasai procedure. Participation by parents is voluntary. Compensation for transportation provided.
IBD Research Registry
Are you 18 years of age or older, and are seeking or already receiving treatment at the UPMC Inflammatory Bowel Disease Center? If so, you may be able to take part in the IBD Research Registry, which is a list of individuals who are interested in having their medical information included in research studies and being contacted about future research studies.