Flu Vaccine Study - Young Adults Aged 18-21
STUDY BASICS
Are you aged 18-21 and have not yet received the 2020-21 flu vaccine? If so, you may be able to participate in a research study to help better understand young adults’ immune response to the flu vaccine. Participants will receive the flu vaccine as a shot or nasal spray. Compensation provided.
STUDY PURPOSE
Getting a yearly flu vaccine can help prevent most cases of the flu—a common viral infection that affects millions of people each year. The flu vaccine is approved by the United States Food and Drug Administration (FDA) to be given as either a shot or as a nasal spray. The purpose of this study is to help researchers learn more about how young adults respond to the flu vaccine given as a shot or a nasal spray and to better understand the body’s protective response against the flu.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 18-21
- Have not yet received the 2020-21 seasonal flu vaccine (starting in August 2020)
- Willing to be randomly assigned to receive either the flu shot or nasal spray
WHAT PARTICIPANTS CAN EXPECT
Study participation involves up to 3 in-person visits. During the first visit, participants will complete a survey and have a blood draw. Participants will also be randomly assigned (like the flip of a coin) to receive either the FluMist vaccine given as a nasal spray or the Flucelvax vaccine given as a shot. Participants will be asked to return one week later and one month later for additional blood draws.
IRB: STUDY19040242D
- Option B Pittsburgh: Immunological Response to Influenza Vaccination in Children, Adolescents, and Young Adults: A RCT of FluMist vs. FlucelvaxMEET THE RESEARCHER

Richard K. Zimmerman
Richard K. Zimmerman, MD, MPH, is a Professor of Family Medicine and Behavioral & Community Health Sciences at the University of Pittsburgh. A graduate of Ohio State University and the University of Minnesota, Dr. Zimmerman’s research interests include barriers to immunization, vaccination schedules, vaccine effectiveness, cost-effectiveness of alternative vaccination strategies, and immune response to influenza vaccines across the age spectrum.
MEET THE COORDINATOR

Katherine Williams
Katherine V. Williams, MD, MPH is a Research Project Coordinator in the Department of Family Medicine. Dr. Williams’ research interests include finding ways to maintain health and prevent disease.