Multi-Modal Study - Bipolar Disorder

STUDY BASICS

Have you been diagnosed with Bipolar Disorder? You may be eligible for a research study to observe the effects of medication on brain activity in adults with and without Bipolar Disorder. If you qualify to participate in the study, pictures of your brain will be taken using 3 types of scanners. Compensation is provided.

STUDY PURPOSE

This research study will examine how medication affects the brain in young adults with Bipolar Disorder and healthy controls without Bipolar Disorder.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 18-35 years old
• Diagnosed with Bipolar Disorder

WHAT PARTICIPANTS CAN EXPECT

Participants will complete 4 study visits. The study procedures include:

• questionnaires about topics like your health history and feelings
• routine health screening like physical exams, blood draws, and EKGs
• urine and saliva tests for drug and alcohol use
• urine pregnancy tests if you have childbearing potential
• Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Positron Emission Tomography (PET) scans of your brain
• computer tasks that may require you to push buttons
• one time use of an oral medication commonly prescribed for ADHD (dextroamphetamine/d-amphetamine)
• overnight medical monitoring at UPMC Western Psychiatric Hospital (WPH) for a minimum of 24 hours and up to a maximum of 48 hours