One-Day Cold-Sleep for Long-Duration Spaceflight
STUDY BASICS
Are you 25-55 years old? You may be eligible for a laboratory research study. This research study will test protocols that can lower activity and metabolism in astronauts during long spaceflights in order to conserve oxygen, food, and reduce the psychological stress from being confined in a spaceship. Compensation provided.
STUDY PURPOSE
Purpose of the study is to identify a method that can lower activity and metabolism in astronauts during long spaceflights in order to conserve oxygen, food, and reduce the psychological stress from being confined in a spaceship for multiple weeks.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 25-55 years old
- Non-smoker
- No sleep disorders or regular use of sleep aids
WHAT PARTICIPANTS CAN EXPECT
This Study requires two visits to a laboratory at the University of Pittsburgh in Oakland and wearing a monitor and completion of a diary for the week before and after the experiment:
- Screening visit that will take about 1 hour
- Wear activity and heart monitor and complete a sleep diary for 1 week
- Laboratory stay for about 30 hours (arrive ~10am and depart ~5pm next day)
- Wear activity and heart monitor and complete a sleep diary for 1 week
Participants will have intravenous catheters for blood draws, wear a number of physiological monitors, and take a sedating medication to sleep overnight while in the laboratory.
IRB: STUDY23050190
- Cold-Sleep for Long-Duration Spaceflight: one-day protocolMEET THE RESEARCHER
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Clifton Callaway
Dr. Callaway is Distinguished Professor, Vice-Chair, and Ronald D. Stewart Endowed Chair in Emergency Medicine Research at the University of Pittsburgh School of Medicine. He completed his PhD in Neuroscience (1992) and MD (1993) at the University of California, San Diego, followed by residency in Emergency Medicine at the University of Pittsburgh (1996). He and partners lead a multidisciplinary clinical service to advance the care of patients after cardiac arrest, with particular focus on promoting recovery from brain injury. Past research includes leadership for multiple clinical trials in emergency and acute care, implementation of therapies used by emergency medical services, and translational research on neurological effects of temperature manipulation. Currently, Dr. Callaway helps lead the clinical coordinating center for SIREN, an National Institutes of Health emergency research trial network of over 75 medical centers that conducts clinical trials in acute care. He has contributed to national and international guidelines for advanced life support since 2008.