Are you the parent of a son who will receive treatment for a medical condition that may result in infertility (inability to have children)? Your child may be able to participate in a research study to develop ways to preserve testicular tissue and possibly preserve fertility.
STUDY PURPOSEThe purpose of this study is to help researchers develop techniques for long-term preservation of testicular function through freezing of testicular tissue and/or cells prior to therapies that are likely to cause infertility (for example, chemotherapy, radiation, surgery). Researchers will store frozen testicular tissue and/or cells for your child as a potential resource in the event he wants to attempt to restore fertility in the future. This study will also provide a portion of your child’s tissue for research to advance the understanding of the best techniques for freezing testicular tissue/cells, and the methods of identifying and removing contaminating cancer cells in testicular tissue.
COULD THIS STUDY BE RIGHT FOR YOUR CHILD?
- Boys age 1-17 who will be undergoing treatment for a medical condition which may result in their infertility (inability to have your own children)
WHAT PARTICIPANTS CAN EXPECTAn outpatient surgical procedure lasting about 1 hour to harvest testicular tissue. The study team will contact you every year by phone or mail to follow medical and fertility status over time. Once your son turns 18, he can decide how he would like to use his tissue.
IRB:STUDY19020220A - Testicular tissue cryopreservation for fertility preservation in patients facing infertility-causing diseases or treatment regimens
MEET THE RESEARCHER
Kyle E. Orwig, PhD, is professor of obstetrics, gynecology, and reproductive sciences at the University of Pittsburgh School of Medicine. Dr. Orwig is also the director of the Fertility Preservation Program of UPMC. Dr. Orwig is an experienced and respected researcher at the Magee-Womens Research Institute (MWRI), where he oversees his own lab. His lab focuses on studying the studies normal development of fertility at a molecular level, to better understand conditions that lead to infertility and develop treatments for them. Dr. Orwig is also the director of the Fertility Preservation Program.