Are you the parent of a teen aged 13-17 who is currently feeling sad, gloomy, down, or depressed? If so, your teen may be able to participate in a research study investigating whether an intervention that targets sleep physiology improves mood. Compensation provided.
Many teens experience depression, a serious mood disorder that causes feelings of intense sadness, lowered energy, lack of interest in activities, academic problems, and withdrawal from others. Standard treatments for depression include antidepressant medications and counseling, but these may take weeks or months to work, or may not work at all. Some studies have shown that blocking a part of sleep that is abnormal in depression can rapidly improve depression symptoms, but this effect is not fully understood.
The purpose of this study is to find out if an intervention that targets the sleep-wake cycle is a safe and effective approach for improving depression symptoms in youth and young adults, and to better understand how sleep affects brain systems related to mood. Researchers hope their findings will lead to better treatments for young adults with depression in the future.
COULD THIS STUDY BE RIGHT FOR YOUR CHILD?
- Ages 13-17
- Currently feeling sad, gloomy, down, or depressed
- No history of bipolar disorder or schizophrenia
- No serious medical or neurological conditions
WHAT PARTICIPANTS CAN EXPECT
After completing an online pre-screening survey, this study begins with an eligibility assessment (in-person or virtual).
If eligible after this visit, your child will be invited to participate in 3 consecutive overnight visits at the UPMC Sleep and Behavioral Neuroscience Center. During these visits, teens will have their sleep monitored and sounds will be played during sleep to alter your sleep physiology. Some participants will be invited to complete brain scans with MRI.
In the week after the final overnight visit, participants will be asked to compete brief online surveys about mood and sleep at home.
IRB:STUDY19040072A - Rapid Antidepressant Effects of Selective Slow-Wave Sleep Deprivation for Depressed Youth
MEET THE RESEARCHER
Adriane M. Soehner, PhD, is an Assistant Professor of Psychiatry at the University of Pittsburgh. A graduate of the University of California, Berkeley, Dr. Soehner’s research investigates the role of sleep in brain development and psychiatric illness.