Brain-Stomach Circuits in Chronic Nausea - Healthy Volunteers

STUDY BASICS

Are you in good physical health and without chronic stomach problems? You may be eligible for a research study to stimulate the brain-stomach connection and to determine how this affects stomach activity.

STUDY PURPOSE

This research study is being performed to learn more about how stimulation of the brain-stomach connection can influence stomach activity.  Results from this study could help researchers better understand how the brain influences the digestive system and help in the development of new methods for diagnosing and treating chronic conditions of the digestive system.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 21-60
• In good physical health and without chronic stomach problems
• BMI (Body Mass Index) less than 30

WHAT PARTICIPANTS CAN EXPECT

This project uses a method of non-invasive brain stimulation (Transcranial Magnetic Stimulation TMS) to stimulate the brain-stomach connection and to determine how this affects stomach activity.

Participants will be asked to not eat food for 2 hours prior to study visits, to drink water during the visit and to sit in a chair while receiving TMS.

Heart and stomach activity and muscle responses will be measured non-invasively with skin electrodes during the testing sessions. 

• Testing sessions last 2 to 4 hours.
• At least one visit, and up to 9 follow-up visits could be scheduled.