Did you have a stroke within the past 6 months and are still experiencing one-sided arm weakness from the stroke? Are 18-80 years old? You may be able to participate in a research study to help find out if non-invasive brain stimulation combined with rehabilitation therapy improves arm weakness. Compensation is provided.
An ischemic stroke happens when a blood clot blocks a blood vessel in the brain. Many people who have had an ischemic stroke experience arm weakness that makes it difficult to perform daily tasks. Although physical therapy can help restore function in the arm for some people, many do not fully recover.
The purpose of this study is to find out if non- invasive brain stimulation combined with rehabilitation therapy improves arm weakness in people who have recently had a stroke. Researchers hope their findings will lead to better ways to treat people experiencing arm weakness following a stroke in the future.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 18-80
- Had an ischemic stroke 1-6 months ago (an ischemic stroke happens when a blood clot blocks a blood vessel in the brain)
- Recent stroke was your first stroke
- Experiencing one-sided arm weakness as a result of your stroke
- Have NOT received botulinum toxin (Botox) injections in the last 3 months
- Do not have seizures
- Do not have a pacemaker or any metallic parts in your body
WHAT PARTICIPANTS CAN EXPECT
Participation in this study includes an initial screening visit to find out if you are eligible. Eligible participants will be randomly assigned (like drawing straws) to one of three study groups. All study groups will receive rehabilitation therapy; some will also receive non-invasive brain stimulation. Participation also includes having a Magnetic Resonance Imaging (MRI) scan of the brain. MRI scans are not invasive and do not use radiation.
IRB: CR02_2018-4092C- TRANScranial direct current stimulation for POst-stroke motor Recovery - a phase II sTudy (TRANSPORT2)
MEET THE RESEARCHER
George Wittenberg, MD, PhD, is a Professor in the Department of Neurology at the University of Pittsburgh. Dr. Wittenberg’s research interests include rehabilitation robotics, transcranial brain stimulation, and brain connectivity as it relates to motor function and rehabilitation.