Do you have obsessive compulsive disorder (OCD) and are between the ages of 18-65? If so, you may be able to participate in a research study to help better understand how the brain works in people with OCD. Eligible participants will have a psychiatric evaluation, a urine drug screen, and fMRI scanning. Compensation is provided.
STUDY PURPOSEObsessive compulsive disorder (OCD) is a mental health condition that causes repeated unwanted thoughts. To get rid of obsessive thoughts, a person with OCD may repeatedly perform tasks such as washing hands, checking appliances, doors, or lights, or cleaning or ordering certain objects. Researchers do not fully understand why some people develop OCD. The purpose of this study is to help researchers better understand how the brain works in people who have OCD. Researchers hope their findings will lead to better ways to diagnose and treat OCD in the future.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 18-65
- Diagnosed with obsessive compulsive disorder (OCD)
- Able and willing to undergo MRI scanning (no non-removable metal in the body, not claustrophobic)
- Fluent in English
- No history of any of the following health conditions: seizures, head injury, stroke, heart disease, dementia, autism, Asperger’s syndrome, or neurological disorders such as Parkinson’s disease and multiple sclerosis
- Do not abuse alcohol or use illicit drugs
WHAT PARTICIPANTS CAN EXPECTThis study involves an initial 2-hour screening visit to find out if you are eligible for the study. The screening visit includes questionnaires, reading and memory tests, medical history, psychiatric evaluation, and providing urine and saliva samples. Eligible participants will be asked to have another 2.5 hour visit during which they will have an MRI scan. MRI scans are not invasive and do not use radiation. In some cases, the screening visit and MRI visit can be combined.
IRB:STUDY19040291A - Identifying circuits underlying abnormal anxiety and reward processing in OCD patients
DURATION: About 4.5 hours
VISITS: 1-2 visits
Oxford Building and UPMC Presbyterian Hospital
Up to $100 + some travel expenses
MEET THE RESEARCHERS
Susanne E. Ahmari, MD, PhD, is an Associate Professor of Psychiatry and director of the Translational OCD Laboratory at the University of Pittsburgh. A graduate of Stanford University Medical School, Dr. Ahmari’s research interests include the intersection of compulsive behaviors and anxiety, neural circuits underlying repetitive thoughts and behaviors, and novel tools for circuit dissection. Her ultimate goal is to identify new treatment targets for OCD and related disorders.
Rebecca B. Price, PhD, is an Assistant Professor of Psychiatry at the University of Pittsburgh and director of the Clinical Application of Neuroscience lab. Dr. Price’s research interests center on the role of neurocognitive factors in the etiology, course, and treatment of depression, anxiety, compulsive behaviors, and suicidality. She is particularly interested in the intersection of clinical and neurocognitive research, and translating basic cognitive and affective neuroscience findings into novel brain-based behavioral and biological interventions.
MEET THE COORDINATOR
Benjamin Panny is a Research Specialist in the Clinical Application of Neuroscience lab at the University of Pittsburgh. After receiving bachelor’s degrees in neuroscience and psychology from the University of Rochester, Benjamin Panny began working in Dr. Price’s research program in late 2017 to investigate new treatments for depressive symptoms. He is broadly enthused by nature and currently interested in the aesthetic qualities of everyday life in relation to reasoning, emotion, and motivation with hopes of better understanding what’s going on.