RESET BP Trial

STUDY BASICS

Do you know your blood pressure? Do you sit too much at work? Men and women ages 21–65 who have a desk job and higher than normal blood pressure (but are not taking blood pressure medication) may be able to participate in a research study to find out if sitting less during the workday can lower blood pressure. Remote visits may be available. Compensation is provided.

STUDY PURPOSE

About 2 in 3 adults in the United States have mildly elevated blood pressure, which may lead to a higher risk of health problems like heart attack and stroke. Medications and exercise can help lower blood pressure, but the condition is often uncontrolled. Researchers think that cutting down on the amount of time spent sitting may help some people lower their blood pressure. The purpose of this study is to find out if reducing long periods of sitting by allowing workers to stand more often and have movement breaks can lower blood pressure and improve heart health. Researchers hope their findings will lead to new treatment strategies for people with high blood pressure.

COULD THIS STUDY BE RIGHT FOR YOU?

• Ages 21-65
• Have blood pressure that is equal to or greater than 120/80
• NOT currently taking blood pressure medication
• Exercise less than 150 minutes per week
• Have a cell phone capable of receiving text messages
• Work at a desk for at least 20 hours per week
• Employed in current job at least 3 months, and plan to stay in the same job for the next 4 months
• Able to obtain consent from work supervisor and physician to participate in the study

WHAT PARTICIPANTS CAN EXPECT

This study involves two initial visits to determine if you meet the blood pressure criteria. If eligible, you will be randomly assigned (like the flip of a coin) to receive an immediate 3-month intervention using a sit-stand desk at your workplace or you may choose to receive the delayed intervention after 3 months. After you are assigned to one of the groups, you will have at least two additional visits. Tests and assessments during the study include blood pressure and vascular measurements, blood draws, questionnaires, and wearing activity monitors.

Remote visits by videoconference may be available for this study.