https://pittplusme.org/study/2814
SONO Sleep Study
STUDY BASICS
Trouble Sleeping? You may be eligible for a research study to examine who responds best to common treatments for insomnia. All participants will receive cognitive-behavioral therapy for insomnia. Some participants will also be eligible for a study comparing a medication (trazodone) to placebo. Participants will be asked to complete screening measures, overnight sleep studies and sleep diaries.
STUDY PURPOSE
The purpose of this voluntary research study is to better understand two common treatments for insomnia in adults with elevated blood pressure.
- Cognitive Behavioral Therapy for Insomnia (CBT-I) will be provided to all study participants.
- Some participants will also be part of a randomized placebo-controlled study of trazodone.
COULD THIS STUDY BE RIGHT FOR YOU?
- Age 18 or older
- Have trouble falling asleep, staying asleep, or waking up too early
- Treated for high blood pressure or have blood pressure > 120/80
WHAT PARTICIPANTS CAN EXPECT
• Attend study visits, including overnight sleep studies
• Participate in CBT-I & may take study medication
• Provide blood, urine, & saliva samples.
IRB: STUDY23120024
- sIRB Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia Phenotypes Based on Objective Sleep Duration: A Sequential Cohort/Randomized Controlled Trial
MEET THE RESEARCHER
Daniel J. Buysse
Daniel J. Buysse, MD, has over 25 years of experience in sleep medicine research and has worked extensively with older patients in sleep and circadian rhythm studies. His main areas of focus include sleep assessment and patient reported outcomes; evaluation and treatment of insomnia; and sleep in aging. He has also investigated sleep in mood disorders, and the interaction between sleep and circadian physiology. This research uses a variety of techniques such as self-report, actigraphy, home and laboratory-based polysomnography, laboratory-based circadian assessments, and functional imaging studies. Dr. Buysse has also conducted clinical trials of behavioral treatment for insomnia.