Are you 18-60 years old? Do you often feel the need to complete unwanted, repetitive behaviors like checking, washing, picking, reassurance seeking, etc.? If so, you may be able to participate in a research study to help better understand brain patterns involved in compulsive behaviors and to measure the effects of non-invasive brain stimulation on compulsive behaviors. Compensation provided.
Compulsive behaviors are unwanted, repetitive behaviors that are triggered by an irresistible urge or a desire to obtain absolute certainty. Common compulsive behaviors include repeatedly checking on things (ex. checking to see if a door is locked), excessive cleaning or handwashing, ordering or arranging things “just so,” repeatedly seeking reassurance, mental or superstitious rituals, and repetitive counting, tapping, or picking. The purpose of this research study is to understand the brain patterns involved in compulsive behaviors and measure the effects of non-invasive brain stimulation on compulsive behaviors. Researchers hope their findings will lead to better treatments for people struggling with these behaviors.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 18-60
- Often feel the need to complete unwanted, repetitive behaviors
WHAT PARTICIPANTS CAN EXPECT
Participation involves 4 visits over a 4-5 week period. Participants will be asked to have the following assessments and procedures:
- Interviews and questionnaires
- A computer task that uses mild electrical shocks (the shocks may be unpleasant but are not painful or dangerous)
- Transcranial Magnetic Stimulation (TMS): TMS involves very brief, noninvasive stimulation of a brain area beneath the left side of your forehead
- fMRI scans: fMRI is a noninvasive brain imaging technique that can identify regions of the brain involved in performing specific tasks (like saying words). The scan does not use injections, radioactivity or x-rays
IRB:STUDY19090219 - Testing the Causal Role of the Orbitofrontal Cortex in Human Compulsive Behavior
MEET THE RESEARCHER
Rebecca B. Price, PhD, is an Assistant Professor of Psychiatry at the University of Pittsburgh and director of the Clinical Application of Neuroscience lab. Dr. Price’s research interests center on the role of neurocognitive factors in the etiology, course, and treatment of depression, anxiety, compulsive behaviors, and suicidality. She is particularly interested in the intersection of clinical and neurocognitive research, and translating basic cognitive and affective neuroscience findings into novel brain-based behavioral and biological interventions.