Have you and your child, aged 8-17, both been diagnosed with bipolar disorder? If so, you and your child may be able to take part in a research study to help better understand bipolar disorder in children, teens, and adults. Participation involves four visits and completing questionnaires and interviews. Children will complete two MRI scans. Compensation provided.
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in feelings of mood, energy, and activity levels, and difficulties carrying out day-to-day tasks (NIMH). Bipolar disorder tends to run in families, which means that children with a parent who has bipolar disorder are much more likely to develop the disorder than those who do not.
The purpose of this study is to compare people with and without bipolar disorder to learn more about the symptoms of bipolar disorder in children, teens, and adults. Researchers hope their findings will lead to earlier diagnosis and treatment for young people at risk for developing bipolar disorder.
COULD THIS STUDY BE RIGHT FOR YOU?
• Age 18 and up
• Parent of a child ages 8-17 years old
• Both parent and child have been diagnosed with bipolar disorder
• Child must be right-handed
WHAT PARTICIPANTS CAN EXPECT
Participation involves 4 visits over the course of 2 years. During the initial 2-3 hour screening visit, you and your child will complete questionnaires and interviews. If you decide to continue in the study, your child will have three additional visits. Each of the MRI visits will last approximately 5 hours, spaced about two years apart. In the second year, there will also be a follow-up in-person interview prior to the final MRI visit. At both MRI visits, your child will undergo testing and have an fMRI (functional magnetic resonance imaging) scan. fMRI is a noninvasive brain imaging technique that can identify regions of the brain involved in performing specific tasks (like saying words). The scan does not use injections, radioactivity or x-rays.
IRB:PRO16040137C - Children of Bipolar Parents: A High Risk Follow Up Study (BIOS) MH 060952-16
DURATION: 2 years
VISITS: 4 visits
Bellefield Towers & UPMC Presbyterian (Oakland)