LB3P: Low Back Pain Research Study
STUDY BASICS
Have you had low back pain for more than 3 months? If so, you may be able to participate in a research study to help better understand the factors that contribute to low back pain. This study involves one in-person visit and eight online sessions over 1 year. Compensation is provided.
STUDY PURPOSE
Pain in the lower back is a common problem and a leading cause of disability, but the causes of low back pain are not fully understood. The purpose of this study is to better understand the factors that contribute to low back pain. Researchers hope their findings may lead to better ways to treat low back pain in the future.
COULD THIS STUDY BE RIGHT FOR YOU?
- Have had low back pain for more than 3 months
- Have received care at a UPMC facility at least once, for any reason
- Willing to provide saliva, urine, and blood samples
- Able to speak and understand English
WHAT PARTICIPANTS CAN EXPECT
Participants will be asked to attend one in-person visit at the beginning of the study and eight online visits. Online visits will take place once a month for the first 6 months, and once every 3 months during the next 6 months. The online visits can be completed in any location with an internet-connected computer or smartphone. Participants will also wear motion sensors for a week and answer daily questions about back pain via a mobile application.
IRB: STUDY20030093
- HEALing LB3P: Profiling Biomechanical, Biological, and Behavioral PhenotypesMEET THE RESEARCHERS

Gwendolyn Sowa
Gwendolyn Sowa, MD, is a Professor and Chair of Physical Medicine & Rehabilitation at the University of Pittsburgh School of Medicine. A graduate of the University of Wisconsin, Dr. Sowa’s research interests include low back pain, molecular biomarkers of low back pain, and mechanobiology of the intervertebral disc.

Nam Vo
Nam Vo, PhD, is an Associate Professor in the Department of Orthopaedic Surgery at the University of Pittsburgh.
A graduate of the University of California at Berkeley and the University of Southern California, Dr. Vo’s research interests include the molecular and cellular processes responsible for intervertebral disc diseases.