TrialNET Pathway to Prevention - Ages 2½ - 17

STUDY BASICS

Are you the parent of a child aged 2 ½-17 who has a relative with type 1 diabetes? Your child may be able to take part in a research study to learn more about the development of type 1 diabetes in children who have a family member with the disease. Children found to be at an increased risk for type 1 diabetes may qualify for additional research studies aimed at preventing or delaying the disease.

STUDY PURPOSE

People with type 1 diabetes are unable to produce insulin, a hormone that helps the body process sugar. As sugar builds up in the blood, it can cause harm to many parts of the body including the eyes, heart, blood vessels, nerves, and kidneys. Children who have a family member with type 1 diabetes are more likely to develop the disease themselves, but researchers do not fully understand this relationship.

The purpose of this study is to help learn more about the development of type 1 diabetes in children who have a family member with the disease. Researchers hope their findings will lead to better ways to identify, prevent, and treat type 1 diabetes in the future.

COULD THIS STUDY BE RIGHT FOR YOUR CHILD?

• Ages 2 ½ - 17

• Have a blood relative who has type 1 diabetes

WHAT PARTICIPANTS CAN EXPECT

This screening involves at least one blood draw at UPMC Children’s Hospital of Pittsburgh or at a lab that is more convenient for you. If preferred, participants may also use a study-provided at-home kit for the blood draw. The TrialNet research team will contact parents whose children may be eligible for additional studies.