PRE-EMPT: Prospective Randomized Evaluation and Management of Premature Atherosclerosis

STUDY BASICS

PRE-EMPT, a clinical research study to find better ways to detect and treat heart disease early—before it strikes. Heart disease is the leading cause of death in the U.S., but we don’t routinely screen for it in younger people. The PRE-EMPT study aims to change that. Participation in PRE-EMPT is for people who do not have known heart disease or diabetes.

STUDY PURPOSE

Heart disease is the leading cause of death in the U.S., but we don’t routinely screen for it in younger people. The PRE-EMPT study aims to change that. PRE-EMPT is not just about risk detection; it’s also about treatment. If plaque is present in the heart arteries, PRE-EMPT will test how best to stop its growth or shrink it, which can prevent heart attacks.

COULD THIS STUDY BE RIGHT FOR YOU?

Participation in PRE-EMPT is for people who do not have known heart disease or diabetes.

You may be a good fit if you: 

• Are a woman aged 40–60 or a man aged 30–50
• Meet certain health criteria based on your medical history, family history, or genetic risk

WHAT PARTICIPANTS CAN EXPECT

As a participant, you will:

• Complete study visits for heart imaging tests
• Be randomly assigned to receive one or both study medicines or a placebo
• Answer surveys and have follow-up visits over 2 years
• Receive your results when your time in the study has concluded