About Heart and Circulation
The continual pumping of the heart provides life with an underlying rhythm as blood is circulated throughout the body. While the heart seems to work tirelessly, some conditions can make its workload much heavier. Cardiac diseases like high blood pressure or atherosclerosis can make it harder to pump blood, putting strain on the heart and increasing the risk of more serious heart problems. Irregularities in the heartbeat, or mechanical difficulties with its valves, can disrupt the heart’s work and make it inefficient. Cardiac researchers seek solutions for these and other concerns, looking for ways to help your heart keep the beat.
The ESSENCE Study
Have you been diagnosed with (by liver biopsy), or are you at high risk of developing (have type 2 diabetes, are obese, and/or have high cholesterol), nonalcoholic steatohepatitis (NASH)? You may be able to participate in a study to evaluate an investigational drug for its ability to treat NASH. This study involves 21 visits and up to 9 phone calls over 5 years. Compensation is provided.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
Referral to Physical Activity Research Study
Are you aged 40-70, don’t regularly exercise, and have been told by a physician that you have one of the following: overweight/obesity, high blood pressure, and/or prediabetes? You may be able to participate in a study to help you increase your activity levels. This study involves completing a computer-based program with tracking tools and goal setting materials. Compensation is provided.
Insomnia and Heart Health Study
Do you have trouble sleeping? Are you between the ages of 18-55? If so, you may be able to participate in a research study to help learn more about the relationship between sleep and heart health in adults with insomnia. Participation involves 3 study visits, including one overnight sleep and heart health assessment. Compensation is provided.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Multimodal Connectome Study – Congenital Heart Disease
Are you an adult between ages 18-60 years old who has Congenital Heart Disease? If so, you may be eligible to participate in a study to help researchers determine if differences in how the brain is formed and how it functions can predict behavior variations in different populations. Must be willing and able to undergo MRI scanning. Involves one study visit. Compensation provided.
Brain Development in Unborn Children – Healthy Volunteers
Are you a pregnant woman in your 3rd trimester whose baby is healthy? If so, you and your baby may be able to participate in a research study to help understand brain development. Study involves MRI scans of your baby’s brain and monitoring of your child’s development. Compensation provided.
RESET BP Trial
Do you know your blood pressure? Do you sit too much at work? Men and women ages 21–65 who have a desk job and higher than normal blood pressure (but are not taking blood pressure medication) may be able to participate in a research study to find out if sitting less during the workday can lower blood pressure. Remote visits may be available. Compensation is provided.