https://pittplusme.org/study/2272
Familial Pathways Study (FamPath): The Role of Inflammation and Stress in Youth Suicidal Behavior
STUDY BASICS
Are you 18-30 years old and currently have depressive symptoms? You may be eligible to participate in a study to learn more about the role of biological markers of suicidality that may run in families and brain inflammation in suicidal behavior in young adults. Studies suggest increased inflammation is associated with suicidal behavior. Compensation provided.
STUDY PURPOSE
This study is being conducted to learn more about the familial transmission of suicidal behavior, and the role of brain inflammation in suicidal behavior in young adults. Studies suggest increased inflammation is associated with suicidal behavior. Neuroinflammation or brain inflammation can result from inflammation directly in the brain or inflammation entering the brain from the blood.
COULD THIS STUDY BE RIGHT FOR YOU?
- 18-30 years old
- currently have depressive symptoms
WHAT PARTICIPANTS CAN EXPECT
- Interviews and questionnaires about physical and mental health
- Body and vital measurements
- Blood, hair, and saliva samples
- Stress task
- Magnetic resonance imaging (MRI), functional Near Infrared Spectroscopy (fNIRS), and positron emission tomography (PET scan)
IRB: STUDY21060193
- 1/2 Inflammation and Stress Response in Familial and Nonfamilial Youth Suicidal Behavior
MEET THE RESEARCHER
Nadine Melhem
Nadine M. Melhem, PhD, MPH, is associate professor of psychiatry at the University of Pittsburgh School of Medicine. Trained in psychiatric genetic epidemiology, Dr. Melhem has a long history of working in research and a special interest in studying the impacts of stress and trauma on children and families.