About Healthy Aging
As the average life span increases, more and more adults are looking for ways to stay healthy as they age. Aging populations face several unique challenges to their mental, emotional, and physical wellbeing and researchers are searching for ways to meet those challenges. From studies investigating neurological conditions like Alzheimer’s disease, to studies of mobility assistance and exercise, researchers want to work with seniors to promote healthier, happier lives in our communities.
Brain Stomach Interaction Study
Are you a healthy adult between the ages of 21-60 that has not had weight loss surgery? You may be eligible for a research study to learn more about how the brain influences muscles and internal organs. This study may help find new ways to diagnose and treat a variety of chronic digestive disorders. Compensation is provided.
The Effects of Fasting on Lipid Metabolic Profile and Bone Metabolism
Are you 25 to 45 years old? Do you have a family history of type 2 diabetes and/or personal history of gestational diabetes (diabetes that develops in pregnancy)? You may be eligible for a study assessing the effects of fasting for one day a week for 3 months. Compensation provided.
Are you a relatively healthy adult between the ages of 40 and 59? If so, you may be able to participate in a research study to help learn more about how the brain relates to heart health. Compensation provided.
Relationship Influences on Sleep, Emotions, and Heart Health (RISE Study)
Are you female or do you identify as female? Are you 40-59 years old? If so, you may be able to take part in a research study to help better understand how different experiences and feelings in relationships are related to heart health and sleep among midlife women. Compensation provided.
MyPaTH Story Booth – COVID-19 Vaccine Stories
Have you thought about being vaccinated for COVID-19 or have you already received your COVID-19 vaccine? Are you interested in sharing your experience? You may be able to participate in a study to help learn more about COVID-19 vaccination experiences. This study involves 1 phone call lasting 45 minutes.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Stress and Heart Health Study
Are you curious about your blood pressure and how susceptible you might be to the effects of stress? Are you 45 years old or older? You might be able to participate in a research study to measure how reactive people are during stress. Compensation is provided.
Estrogen Deficiency Study - Ages 18-40 Premature Ovarian insufficiency
Are you 18-40 with a diagnosis of premature ovarian insufficiency? You may be eligible for a research study investigating the effects of low estrogen on bone health and sleep quality. Participation includes only a single study visit which will include a bone density scan and blood draw. Compensation provided.
Estrogen Deficiency Study - Ages 50-65 years old
Are you 50 to 65 years old and have gone through menopause? You may be eligible for a research study investigating the effects of low estrogen on bone health and sleep quality. Participation includes only a single study visit which will include a bone density scan and blood draw. Compensation provided.
PROTECT Study – People without Depression
Are you 50-90 years old and have never been diagnosed with a psychiatric disorder, such as depression or anxiety? You may be able to participate in a study to help understand why some people become depressed and have thoughts of hurting themselves, while others do not. Participation involves interviews, questionnaires, and computer games. Compensation is provided.
HVTN 142 - Males 18-55
Are you a man 18 to 55 years old and in good health? You may be eligible to participate in a research study to test an experimental vaccine against HIV. This study wants to see if the study vaccine is safe and how a person’s immune system responds to it. Compensation is provided.
Quantitative Sensory Testing Study - Healthy Volunteers
Are you a relatively healthy adult? If so, you may be able to take part in a research study comparing healthy volunteers to individuals who have chronic abdominal pain associated with pancreatitis. Participation involves one study visit. Compensation provided.
NEMO Late-Life Depression Study for a Depressed Older Adult in Your Life
Is an older adult (ages 60 and up) in your life currently depressed? If so, he/she may be eligible to participate in a study to help researchers learn more about how the brain functions during medication treatment for depression. Depressed participant must be a current Pitt+Me participant, or must be willing to join, and the depressed older adult has to answer the study screening questions.
Reducing Inflammation for Greater Health Trial: The RIGHT Study
Are you 70 years old or older? You may be eligible for a research study to test whether a medication that blocks inflammation can improve energy level and walking ability. Compensation is provided.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
The Reading Brain Project – Healthy 18-40 year olds that struggle with reading
Do you struggle with reading? Are you a healthy 18-40 year old? You may be able to participate in a study to better understand how different areas of your brain are important for reading. Eligible participants must be right-handed and willing to commit to coming in for study procedures on several different days. This study involves MRI scanning. Compensation is provided.
Dexterity Study- Low Vision
Are you 55 to 70 years old? Have you been diagnosed with age-related macular degeneration, primary open angle glaucoma, or diabetic retinopathy? You may be eligible to participate in a research study is to learn more about how people with and without vision loss perform coordination tasks. Compensation is provided
National Sports Brain Bank Study
Are you 18 years of age or older? Did you ever participate in contact sports and/or have a concussion? You may be eligible for a research study to create a comprehensive clinical dataset and tissue repository that will allow new insights into long-term brain health after head trauma.
Pittsburgh Vaccine Clinical Trial Unit Registry
Are you interested in vaccine research? If so, you can sign up to be part of the Pittsburgh Vaccine Clinical Trial Unit Registry—a group of people who agree to be contacted when a new vaccine is ready to be tested. Consent to participate in this research study can be done online. Compensation provided if a blood sample is collected.
HCP2 – Connectomics in Brain Aging (CoBrA) Study - African Americans Ages 50 and older
Are you African American and 50 years of age or older? You may be able to participate in a brain imaging study. We want to look at how your environment changes the way your brain works as you age.
Mental Health as a Potential Contributor to Postural Instability in Glaucoma - Glaucoma
Are you 65-85 years old and diagnosed with glaucoma? The Human Movement and Balance Laboratory at the University of Pittsburgh is conducting a research study to better understand balance, gait, mental health, and brain features of glaucoma and how they differ from features found in adults without glaucoma. Compensation provided.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
TAPER (Techniques of APplying vaginal Estrogen for prevention of Recurrent urinary tract infections)
Are you a postmenopausal woman who has had multiple urinary tract infections (UTI) over the past year? You may be eligible for a research study looking at the effects of estrogen cream in the vagina on preventing urinary tract infections. Compensation is provided.
Muscle Impact of Treating Osteoporosis - MITO Study
Are you a woman, age 65 or older with osteoporosis or fracture history? You may be eligible for a research study evaluating impact of FDA-approved osteoporosis medications denosumab (Prolia) and zoledronic acid (RECLAST) on muscle and bone health. Parking provided.
HCP2 – Connectomics in Brain Aging (CoBrA) Study
Are you 50 years of age or older? You may be able to participate in a brain imaging study. We want to look at how your environment changes the way your brain works as you age.
The PREVENTABLE Study
Are you age 75 or older? You may be able to participate in a research study to help find out if taking a statin drug may help older adults live well for longer by preventing dementia, disability, or heart disease. Participation in the study may last up to five years. Currently, all study visits will take place by videoconference and phone. Compensation is provided.
Were you previously diagnosed with COVID-19, and have interest in research? Researchers at the University of Pittsburgh are conducting a research study that will enroll patients with and without persistent symptoms after COVID-19. This is a registry study or registry bank. The goal of this study is to help us understand the symptoms that patients get and what may be causing them.
Decentralized Biobanking "de-bi": An app for tracking research donations
Are you 18 and older and interested what happens to the tumor/tissue/blood you donate for research? This research project is developing an app for those who want to track or learn about their biosample donations and studying patient preferences for feedback about research on their biosamples.
UCSUR Research Registry
The University Center for Social & Urban Research (UCSUR) conducts academic surveys and studies with local residents. Join UCSUR’s Registry to be added to a list of potential participants for medical and non-medical research studies, including studies about quality of life, community issues, current events, etc. Your unique perspective is important!
HIV Prevention Research Registry
Are you interested in learning about HIV prevention research studies taking place at the University of Pittsburgh and UPMC? If so, you can join the HIV Prevention Research Registry. HIV prevention registry members may be contacted by registry staff members about studies for which they appear to qualify. Eligible participants are ages 18 and older.
Pepper Center Research Registry for Older Adults
Are you at least 60 years old? If so, you may be able to take part in the Pepper Center Research Registry to help researchers learn more about aging, mobility, and balance.
REACT!: The Rhythm Experience and Africana Culture Trial II
Are you an African American male or female aged 60-80? Are you interested in attending classes on African dance or Africana culture? You may be able to take part in a research study to find out if participating in these classes improves how you think, feel or function in your day-to-day life. Involves one-hour classes, three days a week, for six months. Compensation provided.
The Rembrandt Study
Were you recently treated for depression and experienced an improvement in your symptoms? Are you aged 60 or older? You may be able to participate in a research study to help better understand why some people experience a return of depression after successful treatment and others do not. Participation includes MRI scanning, memory testing, and other assessments. Compensation is provided.
Familial Pathways Study (FamPath): The Role of Inflammation and Stress in Youth Suicidal Behavior
Are you 18-30 years old and have a history of depression or a mood disorder diagnosis? You may be eligible to participate in a study to learn more about the role of biological markers of suicidality that may run in families and brain inflammation in suicidal behavior in young adults. Studies suggest increased inflammation is associated with suicidal behavior. Compensation provided.
Smartphone Apps for Caregivers
Researchers at Pitt are looking for caregivers of those with spina bifida, spinal cord injury, traumatic brain injury, or cerebral palsy to participate in a research study. Caregivers will take part in group discussions and provide feedback on smartphone apps designed to support individuals with chronic conditions. Compensation provided.
Brain Development Research Study – Ages 18-26
Are you a healthy 18-26 year old? You may be able to participate in a study to understand how our brain changes as we develop into adults. This study involves completing questionnaires, playing computer games, and undergoing brain and EEG scans. Compensation is provided.
Women’s Biome Project – Recent Normal Mammogram
Are you a postmenopausal woman aged 55-64? Did you have a normal mammogram at a UPMC facility in the past three months? You may be able to participate in a research study to learn more about how the microbiome (the community of bacteria and microscopic organisms that live in our bodies) affects women’s health. Eligible participants have never been diagnosed with cancer. Compensation is provided.
FIT BOLD Research Study
Did you recover from depression in the past two years? Are you age 60 or older? You may be able to participate in a research study to help better understand how lifestyle modification affects the brain in recently depressed older adults. Participants will take part in one of two healthy lifestyle programs, each facilitated by a personal coach. Compensation and travel reimbursement is provided.
Senior Moments Study – Healthy Volunteers Needed!
Do you experience occasional “senior moments” with your memory? Are you an African American man or woman who is at least 60 years old? Do you have a family member or close friend who can accompany you on study visits? If so, you may be able to participate in a research study to help identify memory problems at the earliest stages of Alzheimer’s disease.
15104 Seniors Project
Are you or someone you know aged 65 or older and live in the 15104 ZIP code? Learn about a research project that is studying healthy aging and what factors allow people to preserve their ability to think, remember, and solve problems over time. This study involves a yearly interview of up to 3 ½ hours for up to 5 years. Compensation provided.
Do you plan on receiving a COVID-19 vaccine? You may be able to participate in a study to help determine the effect of the vaccine on autoimmune disease. This study involves 4 visits over 6 months. Eligible participants must not be diagnosed with any autoimmune disorder.
Are you age 60 or older? Did your spouse or partner pass away in the past 12 months? You may be able to participate in a research study to help learn more about health behaviors and mood in bereaved older adults. This study involves 7 visits (online or by phone) over 15 months and includes recording daily activity, mood, diet, and sleep behaviors for 12 weeks. Compensation is provided.
Research Attitudes in Alzheimer’s Disease
Are you ages 50-70? Have you taken a commercial genetic test, such as 23andMe®? Have results from that test shown that you have an increased risk of developing Alzheimer's disease? If so, you may be able to participate in a study to help determine your interest in participating in Alzheimer’s disease research studies. This study involves completing a questionnaire over the phone.
ForAging: Facilitating Optimal Routines in Aging
Are you age 60 or older and do you have difficulty managing daily tasks such as shopping, paying bills, managing medications, etc.? If so, you may be eligible to participate in a research study to help find out if regular sessions with a rehabilitation specialist can help older adults improve their performance of daily activities. Compensation is provided.