STUDY BASICS
Are you a healthy adult, 18 to 35 years old? You may be eligible for a research study to observe the effects of medication on brain activity in adults with and without Bipolar Disorder. If you qualify to participate in the study, pictures of your brain will be taken using 3 types of scanners. Compensation is provided.
STUDY PURPOSE
This research study will examine how medication affects the brain in young adults with Bipolar Disorder and healthy controls without Bipolar Disorder.
COULD THIS STUDY BE RIGHT FOR YOU?
- Ages 18-35 years old
- No personal psychiatric history
WHAT PARTICIPANTS CAN EXPECT
Participants will complete 4 study visits. The study procedures include:
- questionnaires about topics like your health history and feelings
- routine health screening like physical exams, blood draws, and EKGs
- urine and saliva tests for drug and alcohol use
- urine pregnancy tests if you have childbearing potential
- Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Positron Emission Tomography (PET) scans of your brain
- computer tasks that may require you to push buttons
- one time use of an oral medication commonly prescribed for ADHD (dextroamphetamine/d-amphetamine)
IRB: STUDY24040069B
- Linking mania/hypomania with abnormal reward expectancy- and approach-related neural network activity and dopamine releaseMEET THE RESEARCHER
Mary Phillips
Mary L. Phillips, MD, is Professor in Psychiatry and Translational Science and Director of the Mood and Brain Laboratory at the University of Pittsburgh. A graduate of the University of Cambridge, Dr. Phillips’ research focuses on the identification of neural correlates that underlie symptoms of specific abnormalities in emotion processing in people with mood disorders.