About Immune System/Infections
By deterring and defeating infections, the immune system defends the body from threats. Some diseases, such as HIV/AIDS, impair or disable the immune system, making the body more vulnerable to disease. Other conditions, such as rheumatoid arthritis and lupus, can cause the immune system to malfunction and begin to attack the body. Allergic reactions are excessive immune system responses as well, triggered by medications or foods or other foreign substances. By studying the immune system, researchers try to help the body’s defenses hold the line in the fight against disease and to prevent the body from turning those defenses on itself.
MyPaTH Story Booth – COVID-19 Vaccine Stories
Have you thought about being vaccinated for COVID-19 or have you already received your COVID-19 vaccine? Are you interested in sharing your experience? You may be able to participate in a study to help learn more about COVID-19 vaccination experiences. This study involves 1 phone call lasting 45 minutes.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
HIV Vaccine Research Study
Are you 18 to 55 years old and living with HIV? You may be eligible for a research study to test an experimental HIV vaccine combined with an experimental adjuvant to see how the immune responses change among participants who do an antiretroviral analytical treatment interruption (ATI) compared to those who do not. Compensation is provided.
VX22-264-101 - Type 1 Diabetes Treatment Study
Do you have Type 1 Diabetes? Are you 18-65 years old? You may be eligible for a research study to determine whether the VX-264 implant can improve glucose control. Compensation is provided.
Lung Research Study - men and women living with HIV
Are you 40 to 75 years old and living with HIV? Do you have chronic obstructive pulmonary disease (COPD) or emphysema? You may be eligible to participate in a research study to determine whether HIV-related COPD is associated with changes in the lung cell type. Compensation is provided.
HVTN 142 - Males 18-55
Are you a man 18 to 55 years old and in good health? You may be eligible to participate in a research study to test an experimental vaccine against HIV. This study wants to see if the study vaccine is safe and how a person’s immune system responds to it. Compensation is provided.
Pittsburgh Vaccine Clinical Trial Unit Registry
Are you interested in vaccine research? If so, you can sign up to be part of the Pittsburgh Vaccine Clinical Trial Unit Registry—a group of people who agree to be contacted when a new vaccine is ready to be tested. Consent to participate in this research study can be done online. Compensation provided if a blood sample is collected.
Reproductive Outcomes of Women with Rheumatic Diseases
Are you an 18-44 year old woman who is diagnosed with an autoimmune disease (also called rheumatic disease)? Do you take medication for your disease? You may be able to participate in a research study to learn more about reproductive decisions in women who have autoimmune diseases. This study involves completing a questionnaire once every three months. Compensation is provided.
All of Us Pennsylvania Research Program
All of Us wants at least one million people to join. Your participation can help shape the future of health for generations to come. People who join will share information. This might be about their health, habits, and what it’s like where they live. It might also be about family history and genes. By looking for patterns, researchers may learn more about what affects people’s health.
If you have tested positive for Covid-19 in the last 3 days and are considered at standard risk for severe COVID-19 and have none of the risk factors that would put you at higher risk of disease progression you may be able to participate in a study to determine the safety and effectiveness of an experimental medication for COVID-19.
Reproductive Autonomy in the Healthcare Setting - Black patients with Lupus
Are you a Black person currently pregnant or trying to become pregnant? Have you been diagnosed with lupus? You may be able to participate in a research study to explore your thoughts and feelings around your reproductive health. Compensation is provided.
Were you previously diagnosed with COVID-19, and have interest in research? Researchers at the University of Pittsburgh are conducting a research study that will enroll patients with and without persistent symptoms after COVID-19. This is a registry study or registry bank. The goal of this study is to help us understand the symptoms that patients get and what may be causing them.
7T COVID Study –Participants with Severe Illness (NOT COVID-19)
Are you 45-80 years of age? Were you admitted to a UPMC hospital for a severe infection (such as pneumonia or skin infection) that was not COVID-19 between March 2020 - July 2022? You may be able to participate in a study that involves completing questionnaires, undergoing psychological testing, providing a blood sample, and undergoing a specialized MRI scan of the brain. Compensation is provided.
HIV Prevention Research Registry
Are you interested in learning about HIV prevention research studies taking place at the University of Pittsburgh and UPMC? If so, you can join the HIV Prevention Research Registry. HIV prevention registry members may be contacted by registry staff members about studies for which they appear to qualify. Eligible participants are ages 18 and older.
7T COVID Study
Are you 45-80 years of age? Were you admitted to a UPMC hospital for COVID-19 between March 2020 - July 2022? You may be able to participate in a study to identify the effects of COVID-19 infection on the brain. This study involves completing questionnaires, undergoing psychological testing, providing a blood sample, and undergoing a specialized MRI scan of the brain. Compensation is provided.
HIV Research Registry
Are you interested in studies related to the treatment and prevention of HIV/AIDS and related conditions? HIV Research Registry members may be contacted by registry staff about studies for which they appear to qualify. Eligible participants are ages 18 and older.
HIV Vaccine Study
Are you HIV-positive and doing well on your HIV medications? Are you aged 18-65? If so, you may be eligible to participate in a research study to find out if a vaccine made from a person’s own white blood cells can safely strengthen the body’s immune system. Participation lasts 80 weeks. Compensation and parking vouchers/bus tickets provided.
NETI Research Study
Are you a person living with HIV? Have you been taking antiretroviral drugs that have been controlling your HIV for at least two years? You may be able to participate in a research study to find out if an investigational vaccine called Trimer 4571 is safe and well tolerated in people living with HIV and if it will help the body’s immune system respond to HIV. Compensation is provided.