About Lungs and Breathing
The lungs are the main organs in the respiratory system and control breathing. The interior of a lung resembles an upside-down tree; passages at the top of the lungs branch off repeatedly, splitting into smaller and smaller passages before ending in tiny sacs called alveoli. The alveoli let blood come into contact with air, allowing the blood to pick up oxygen and release carbon dioxide. If the passages of the lungs become inflamed, as is the case with asthma, they can swell and make it hard to breathe. Particulates in the air, whether caused by smog or cigarettes, can clog the lungs and limit the oxygen they can take in. Alveoli can also become swamped with fluids like mucus; this can be a major concern for people with cystic fibrosis or pneumonia.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
All of Us Pennsylvania Research Program
All of Us wants at least one million people to join. Your participation can help shape the future of health for generations to come. People who join will share information. This might be about their health, habits, and what it’s like where they live. It might also be about family history and genes. By looking for patterns, researchers may learn more about what affects people’s health.
IMSA 2 Healthy Volunteers
You may be able to participate in a research study that is being done to learn more about the way asthma impacts your airway, and how these changes compare to changes in your clinical condition and breathing tests.
Lung Health Cohort Study
Are you a healthy African American or Hispanic ages 25-35 years old? You may be able to participate in a research study to understand how and why lung disease develops. Compensation is provided.
Lung Research Study - men and women living with HIV
Are you 40 to 75 years old and living with HIV? Do you have chronic obstructive pulmonary disease (COPD) or emphysema? You may be eligible to participate in a research study to determine whether HIV-related COPD is associated with changes in the lung cell type. Compensation is provided.
Dupilumab and MCC Study
Do you have moderate to severe asthma? Are you at least 18 years old? You may be eligible for a research study looking at mucus accumulation and obstruction in the airways of moderate to severe asthmatics. Compensation is provided.
Volunteer for Asthma - AIR (Asthma Institute Research Registry)
Do you have asthma? You may be able to participate in a registry that aims to accelerate improve the understanding of asthma in Western Pennsylvania. We are asking people with asthma in our community to help us learn more about their own asthma, with the goal of improving to help us try to improve care for all asthmatics.
IMSA 2 Study
This is a research study that is being done to learn more about severe asthma by comparing people with severe asthma to those with milder forms of asthma and people without asthma, over time.
Do you have a cardiovascular disease (with or without Type 2 Diabetes)? Are you 18 years old or older? You may be able to participate in a research study to see the safety of study drug LY3437943.
TOPMAS - Transcript/Omics for Precision Medicine in Asthma (Adult Arm)
Are you 18-21 years old? Do you experience mild to severe persistent asthma? You may be able to participate in a research study to better manage asthma in patients with severe disease. Compensation is provided.
Do you have COPD? You may be able to participate in a study to evaluate the ability of a study drug, called benralizumab, to improve lung function and reduce the rate of moderate and severe COPD flare-ups. Eligible participants are 40-85 years old and are current or ex-smokers. Participation will last about 56 weeks and will involve several visits. Reimbursement for visits and parking/bus voucher.
7T COVID Study –Participants with Severe Illness (NOT COVID-19)
Are you 45-80 years of age? Were you admitted to a UPMC hospital for a severe infection (such as pneumonia or skin infection) that was not COVID-19 between March 2020 - July 2022? You may be able to participate in a study that involves completing questionnaires, undergoing psychological testing, providing a blood sample, and undergoing a specialized MRI scan of the brain. Compensation is provided.
Genomic Approaches to Recurrent Pregnancy Loss Study
Are you a woman between the ages of 18 and 37 who has experienced a pregnancy loss? You may be able to participate in a study that hopes to better understand the genetic basis of recurrent pregnancy loss.
Spinal Cord Stimulation for the treatment of motor deficits in people with Spinal Muscular Atrophy
Are you affected by Spinal Muscular Atrophy? You may be able to participate in a research study using spinal cord stimulation (SCS), an approved clinical therapy for pain syndromes that do not respond to drugs. Unexpectedly, SCS has shown the ability to promote the recovery of leg motor function in people with complete motor paralysis in consequence of spinal cord injury years after injury.
Emphysema/COPD Research Registry
Are you an adult who has been diagnosed with Chronic Obstructive Pulmonary Disease (COPD) or emphysema? You may be able to participate in the Emphysema/COPD Research Registry. Compensation may be provided.