About Lungs and Breathing
The lungs are the main organs in the respiratory system and control breathing. The interior of a lung resembles an upside-down tree; passages at the top of the lungs branch off repeatedly, splitting into smaller and smaller passages before ending in tiny sacs called alveoli. The alveoli let blood come into contact with air, allowing the blood to pick up oxygen and release carbon dioxide. If the passages of the lungs become inflamed, as is the case with asthma, they can swell and make it hard to breathe. Particulates in the air, whether caused by smog or cigarettes, can clog the lungs and limit the oxygen they can take in. Alveoli can also become swamped with fluids like mucus; this can be a major concern for people with cystic fibrosis or pneumonia.
Do you have COPD? You may be able to participate in a study to evaluate the ability of a study drug, called benralizumab, to improve lung function and reduce the rate of moderate and severe COPD flare-ups. Eligible participants are 40-85 years old and are current or ex-smokers. Participation will last about 56 weeks and will involve several visits. Reimbursement for visits and parking/bus voucher.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Spinal Cord Stimulation for the treatment of motor deficits in people with Spinal Muscular Atrophy
Are you affected by Spinal Muscular Atrophy? You may be able to participate in a research study using spinal cord stimulation (SCS), an approved clinical therapy for pain syndromes that do not respond to drugs. Unexpectedly, SCS has shown the ability to promote the recovery of leg motor function in people with complete motor paralysis in consequence of spinal cord injury years after injury.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
Are you 40-75 years old and diagnosed with COPD? You may be able to participate in study to evaluate the ability of the Nuvaira™ Targeted Lung Denervation Therapy to improve lung function and reduce the number and severity of COPD flare-ups. Eligible participants do not currently smoke. Participation in this study will last 5 years and includes multiple visits. Compensation provided.
Emphysema/COPD Research Registry
Are you an adult who has been diagnosed with Chronic Obstructive Pulmonary Disease (COPD) or emphysema? You may be able to participate in the Emphysema/COPD Research Registry. Compensation may be provided.
Airway Clearance in MDS
Are you a male between the ages of 18-21 who has been diagnosed with Duchenne or Becker muscular dystrophy? If so, you may be able to participate in a research study to see if simple breathing tests can help determine how well you can clear your airways of mucus. Compensation provided.