Respiratory Syncytial Virus (RSV) Research Study for Pregnant Women - 16-17

STUDY BASICS

Are you the parent of a teen that is currently pregnant? Your teen can help us to learn how the Respiratory Syncytial Virus (RSV) Vaccine protects infants. Pediatricians at the University of Pittsburgh are conducting a research study to better understand how well and how long protection from Respiratory Syncytial Virus (RSV) vaccine lasts for babies. Participants are compensated for their time.

STUDY PURPOSE

This study is comparing RSV protection in babies born to mothers who:

• Received RSV vaccine in this pregnancy
• Received RSV vaccine in a prior pregnancy and are now pregnant again
• Did not receive the RSV vaccine

To understand:

• How much protection babies have at birth
• How long that protection lasts through early infancy
• Whether babies of mothers vaccinated in a prior pregnancy have the same protection as those vaccinated in the current pregnancy

COULD THIS STUDY BE RIGHT FOR YOUR CHILD?

• Pregnant
• ≥ 16 years and ≤ 17 years

• Planning to deliver at UPMC Magee-Womens Hospital
• Willing to provide maternal, cord blood and infant blood samples at delivery and 4 months of age

WHAT PARTICIPANTS CAN EXPECT

 If your teen participates, they may sign the consent form as early as 20 weeks gestation. The study team would then have a screening visit, virtually or in person - once they are >=35 weeks pregnant to confirm final eligibility, then have two additional visits at delivery and at 4 months of age. At the delivery visit, the study team will collect a small blood sample from your child and breastmilk if your child is breast feeding. The study team will also collect cord blood from the baby.  At the 4-month-visit, they will collect a small blood sample from both the 4-month-old baby and from your teen. If your teen is still breastfeeding, they will also collect a sample of breast milk.