PREPARE 2 - Pregnant Participants
STUDY BASICS
Are you interested in non-opioid pain management options for recovery after your cesarean delivery? You may be eligible for a research study to better understand how patients who have just delivered a baby via c-section metabolize ketamine and how this infusion may help reduce symptoms of postpartum depression and pain. Compensation is provided.
STUDY PURPOSE
The PREPARE 2 study aims to better understand how patients who have just delivered a baby via c-section metabolize ketamine, which is a non-opioid drug that is commonly used for surgical procedures. Additionally, the study is investigating how this infusion may help reduce symptoms of postpartum depression and pain.
COULD THIS STUDY BE RIGHT FOR YOU?
- A woman of at least 18 years of age
- Delivering your baby via c-section at UPMC Magee Women’s Hospital
- Delivering your baby at 37 weeks’ gestational age or greater
WHAT PARTICIPANTS CAN EXPECT
- Complete a series of questionnaires prior to your surgery
- Receive an infusion of ketamine for pain management after your cesarean delivery
- Complete weekly questionnaires about your mood and pain throughout the first 3 months postpartum
IRB: STUDY22100019A
- Ketamine Pharmacokinetics and Pharmacodynamics for Pain and Postpartum Depression after Cesarean DeliveryMEET THE RESEARCHER

Grace Lim
Grace Lim, MD, MS, is a physician scientist and board-certified obstetric anesthesiologist who has dedicated her clinical, educational, and research career to improving health and outcomes for mothers and babies. Dr. Lim’s research focuses on acute clinical care and interventions in periods of stress and trauma, such as childbirth or surgery, so that long-term recovery and maternal and neonatal health are optimized.