Dopaminergic Dysfunction in Late-Life Depression - Control Arm

STUDY BASICS

Are you an adult 60 years old or older without depression? You may be eligible for a research study to better understand how the brain’s dopamine system may contribute to depression in older adults. Compensation is provided.

STUDY PURPOSE

The purpose of this research study is to better understand how the brain’s dopamine system may contribute to depression in older adults. Dopamine is a neurotransmitter, a chemical messenger released by nerve cells. Some medications used to treat depression affect dopamine but most do not. In this study you will have tests of your memory, concentration, thinking, and walking. You will have brain scans using magnetic resonance imaging (MRI). We are performing these scans to understand more about how the brain’s dopamine system may be different in older adults who are depressed.  

COULD THIS STUDY BE RIGHT FOR YOU?

Eligible participants:

• Are ages 60 and older 
• Have no history of depression 

WHAT PARTICIPANTS CAN EXPECT

After an initial visit to determine if you are eligible for the study, you will have 2 in-person visits. You will have 1 MRI brain scan. During the baseline period, we administer tests of your memory, concentration and thinking. You will also have a blood draw.