Saliva and PPCS – Orthopaedically Injured Arm
STUDY BASICS
Has your child had an injury, such as a sprain, strain, or fracture in the past 7 days? Is your child 11-17 years old and has NOT had a previous brain injury or other psychiatric disease? You and your child may be able to participate in a research study to help us learn more about head injuries and biomarkers in adolescent athletes. Compensation is provided.
STUDY PURPOSE
The purpose of this study is to test the ability of a saliva test to identify biomarkers associated with concussion types or what are called profiles, in adolescent athletes. The study will also see how adolescents recover from a concussion, and if there are any changes in the biomarkers of their saliva as they heal.
We will compare one group of study subjects who have been diagnosed with a concussion to a group of study subjects who do not have a concussion as well as a group that also does not have a concussion but has orthopedic injuries within the last 7 days to match our concussed participant group.
COULD THIS STUDY BE RIGHT FOR YOUR CHILD?
Eligible participants:
- Are 11-17 years old
- Have received an orthopaedic injury in the last 7 days
WHAT PARTICIPANTS CAN EXPECT
There is 1 visit in the study. Your child will be asked to complete several tests for the study as well as provide saliva samples. For some tests, your child will answer on a computer (multiple choice and fill in the blank). Other tests will involve the researchers testing your child's balance.
IRB: STUDY21080172B
- sIRB - Rapid saliva test for diagnosis of mTBI and prognosis of Persistent Post-Concussion Symptoms (PPCS) in children and adultsMEET THE RESEARCHER

Anthony Kontos
Dr. Anthony P. Kontos is Research Director for the UPMC Sports Medicine Concussion Program and Professor in the Departments of Orthopaedic Surgery and Sports Medicine and Rehabilitation at the University of Pittsburgh. He has specialized in concussion research for 18 years and has over 220 peer-reviewed publications and over 380 professional presentations. His research is funded by Centers for Disease Control and Prevention, Department of Defense, National Institutes of Health, and National Football League and focuses on active, precision treatments and clinical trials; risk factors; neurocognitive/neuromotor effects; psychological issues; and concussion in military, pediatric, and sport populations. Dr. Kontos is a fellow and past-president of the Society for Sport, Exercise, & Performance Psychology of the American Psychological Association, and a fellow of the National Academy of Kinesiology, Association for Applied Sport Psychology, and Eastern Psychological Association. He also co-authored (with Dr. Collins) Concussion: A Clinical Profile Based Approach to Assessment and Treatment.