CURRENT STUDIES THAT MAY INTEREST YOU


HCC 19-120: Advanced Prostate Cancer Study

Have you been diagnosed with metastatic castration-resistant prostate cancer? If so, you may be eligible for a research study to help find out if combining two investigational drugs, called niraparib and JNJ-63723283, is effective as a treatment for metastatic prostate cancer. Reimbursement provided for travel and meals for each visit.

Age Range
AGE:   18 and up

Duration VISITS:  Multiple visits
Location LOCATION:  UPMC Hillman Cancer Center sites in Monroeville, Upper St. Clair, Passavant, Shadyside, & Arnold Palmer Mt. View (Greensburg), St. Margaret


HCC 19-146: Metastatic Prostate Cancer Study

Have you been diagnosed with metastatic prostate cancer? If so, you may be eligible for a research study to see how often men with metastatic prostate cancer have DNA-repair defects and to provide the results to both you and your study doctor. This study involves 1 visit where you will provide either a saliva or blood sample for genetic research.

Age Range
AGE:   18 and up

Duration VISITS:  1
Location LOCATION:  Various UPMC Cancer Center locations


HCC 18-023 (EA8153)

Have you been diagnosed with prostate cancer that has spread? Have you already undergone treatment with hormone therapy and docetaxel (chemo drug)? If so, you may be eligible to participate in a study to help researchers test any good or bad effects of using the chemotherapy drug cabazitaxel (Jevtana) combined with standard of care treatment compared to people on standard of care treatment alone.

Age Range
AGE:   18 and up

Duration DURATION:  Up to 5 years
Location LOCATION:  UPMC Hillman Cancer Centers


HCC 19-042: COSMIC-313 Study – Advanced Kidney Cancer

Do you have advanced or metastatic kidney cancer (also called renal cell carcinoma) that has not yet been treated? If so, you may be eligible for a research study to help find out if the three-drug combination of cabozantinib, nivolumab, and ipilimumab is a safe and effective treatment for people with advanced or metastatic kidney cancer.

Age Range
AGE:   18 and up

Duration DURATION:  About 15-21 months
VISITS:  Multiple
Location LOCATION:  UPMC Hillman Cancer Center – Shadyside, Monroeville, Greensburg, Upper St. Clair, UPMC Passavant


MyPaTH Story Booth – COVID-19 Stories

Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.

Age Range
AGE:   18 and up

Duration DURATION:  About 45 minutes
VISITS:  No in-person visits
Location LOCATION:  By phone


HCC 19-059 - ICONIC Study

Do you have a rare genitourinary (GU) tumor? If so, you may be eligible to participate in a study to help researchers test the good and bad effects of three combined cancer drugs, called cabozantinib, nivolumab, and ipilimumab, that are FDA-approved individually, but not in combination.

Age Range
AGE:   18 and up

Duration DURATION:  24 months of treatment & a follow-up period
VISITS:  Multiple
Location LOCATION:  UPMC Hillman Cancer Centers in Greensburg, Monroeville, Passavant & Shadyside


HCC 19-184: Advanced Prostate Cancer Study

Have you been diagnosed with metastatic castration-resistant prostate cancer? If so, you may be eligible for a research study to help find out what effects, good and bad, that an investigational drug called tazemetostat has on you and your prostate cancer. Reimbursement for study visits is provided.

Age Range
AGE:   18 and up

Duration DURATION:  28 months
VISITS:  Multiple visits
Location LOCATION:  UPMC Hillman Cancer Center - Shadyside


MyPaTH Story Booth 2.0

Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.

Age Range
AGE:   18 and up

Duration DURATION:  45 minutes
VISITS:  1 visit or phone call
Location LOCATION:  By phone


HCC 19-054: TALAPRO-2 Study – Advanced Prostate Cancer

Have you been diagnosed with metastatic castration-resistant prostate cancer? If so, you may be eligible for a research study to help find out if adding an investigational drug called talazoparib to an existing, FDA-approved prostate cancer drug called enzalutamide is a safe and effective treatment.

Age Range
AGE:   18 and up

Duration DURATION:  Varies
VISITS:  Multiple
Location LOCATION:  UPMC Hillman Cancer Center: Shadyside, Altoona, Greensburg, Monroeville, Passavant, Uniontown, Upper St. Clair, Washington


UPCI #17-095 – Prostate Cancer Study

Did you have surgery for high-risk prostate cancer and currently have a rising PSA (prostate-specific antigen) level? If so, you may be eligible to participate in a research study to help compare three different hormonal treatments to find out which one is the most effective for lowering PSA levels and slowing or stopping the return of prostate cancer.

Age Range
AGE:   18 and up

Duration DURATION:  Varies
VISITS:  Multiple
Location LOCATION:  UPMC Hillman Cancer Centers in Altoona, Monroeville, & Shadyside


HCC 18-040

Have you been diagnosed with relapsed (comes back) or refractory (did not get better) multiple myeloma? If so, you may be eligible to participate in a study to help researchers test whether an investigational (experimental) drug called venetoclax combined with dexamethasone works better than the combination of pomalidomide and dexamethasone to treat multiple myeloma. Compensation provided.

Age Range
AGE:   18 and up

Location LOCATION:  UPMC Cancer Center


Squamous Cell Carcinoma of the Lower Extremities Study

Have you been diagnosed with squamous cell carcinoma (SCC) on your lower extremity (below the knee)? If so, you may be eligible to participate in a study to help researchers determine if the need for surgical treatment of SCC can be eliminated by injecting a solution of a chemotherapeutic drug.

Age Range
AGE:   18 and up

Duration VISITS:  5 visits
Location LOCATION:  UPMC St. Margaret Dermatology


Experiences of Men with Cancer - Questionnaire

Are you an adult male with a past or current cancer diagnosis? If so, you may be able to participate in a research study to help better understand how men with cancer stand up for themselves (called “self-advocacy”). Involves completing questionnaires (paper or online) that will take about 30-45 minutes. Compensation provided.

Age Range
AGE:   18 and up

Duration DURATION:  30-45 minutes
Location LOCATION:  Multiple locations


Experiences of Men with Cancer – Interview

Are you an adult male with a past or current cancer diagnosis? If so, you may be able to participate in a research study to help learn more about how men with cancer stand up for themselves (called “self-advocacy”). Involves 3 interviews over 6 months. Compensation provided.

Age Range
AGE:   18 and up

Duration DURATION:  6 months
VISITS:  1-2 visits, plus 2 phone calls
Location LOCATION:  UPMC Hillman Cancer Center, UPMC Passavant, or a location of your choosing


HCC 18-028 – Avmacol® Effects in Previously Treated Tobacco-Related Head and Neck Cancers

Have you been successfully treated for a tobacco-related head and neck cancer in the past five years? If so, you may be able to participate in a research study to help learn more about the effects of a dietary supplement called Avmacol®. Avmacol is made up of broccoli seed, broccoli sprout extract, and vitamin C, and may help reduce inflammation and boost the immune system. Compensation provided.

Age Range
AGE:   18 and up

Duration DURATION:  4 months
VISITS:  8-9 visits
Location LOCATION:  UPMC Hillman Cancer Center or UPMC Eye & Ear Institute


Fertility Preservation Study - Adults

Will you receive treatment for a medical condition that may result in your infertility, and want to preserve your ovarian tissue to possibly allow you to have your own children in the future? You may be able to take part in a research study to develop techniques for long-term preservation of ovarian function through freezing of ovarian tissues.

Age Range
AGE:   18 - 40

Duration VISITS:  2 visits, and yearly follow-up calls/mail
Location LOCATION:  Oakland


Fertility Preservation Study for Adult Men

Are you a man who will receive treatment for a medical condition that may result in infertility (inability to have your own children)? You may be able to participate in a research study to develop ways to preserve testicular tissue and possibly preserve fertility.

Age Range
AGE:   18 and up

Duration VISITS:  1 study visit and annual follow-up calls
Location LOCATION:  Magee-Womens Hospital of UPMC


Effects of Chemotherapy on Sperm Cells

Are you a man age 18-50 who is scheduled to undergo treatment with chemotherapy for a medical condition? If so, you may be able to participate in a research study to find out if the sperm collected shortly after starting chemotherapy is safe and effective for future use.

Age Range
AGE:   18 - 50

Duration VISITS:  2 visits
Location LOCATION:  UPMC Magee Womens Hospital



RELATED RESEARCH AREAS:
  Cancer