About Endocrine System
The endocrine system is made up of different glands which release hormones. Hormones, chemical messengers in the body, play a role in several functions. They regulate digestion, control sexual characteristics and reproduction, initiate growth, increase alertness, relieve stress, and much more. If hormones aren’t produced or processed properly, other organs may not be able to function. For example, diabetes, when the pancreas cannot produce insulin properly, can cause damage to the eyes, kidneys, nervous system, heart, and blood vessels. Other endocrine conditions can affect growth, sexual drive and reproductive abilities, weight regulation, and mood.
Referral to Physical Activity Research Study
Are you aged 40-70, don’t regularly exercise, and have been told by a physician that you have one of the following: overweight/obesity, high blood pressure, and/or prediabetes? You may be able to participate in a study to help you increase your activity levels. This study involves completing a computer-based program with tracking tools and goal setting materials. Compensation is provided.
Evaluation of Flash Continuous Glucose Monitoring to Reduce Hyperglycemia in People with T2 Diabetes
Do you have type 2 diabetes with an A1c from 7.5% and 12%? Not used a continuous glucose meter in the last 3 months? Not on insulin, glipizide or glimepiride? You may be able to participate in a study to assess the impact of the FreeStyle Libre system on HbA1c, body weight, sensor utilization, blood sugar and other health measures.
GLADIATOR STUDY- A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual β-cell Function (LDX0319)
Are you 18-45 years old and have you been newly diagnosed with Type 1 diabetes (first insulin dose within 100 days)? You may be able to participate in a study to find out if an investigational drug called ladarixin is safe and effective and if it is capable of slowing down the progression of type 1 diabetes. Study participation involves about 12 visits, up to 2 years. Compensation is provided.
Type 1 Diabetes Islet Cell Infusion Research Study
Are you 18-65 years old? Have you been diagnosed with type 1 diabetes? Do you have documented severe low blood sugar (hypoglycemia) and impaired hypoglycemic awareness? You may be eligible to participate in a research study to evaluate whether one or two doses of insulin producing cells can provide better control of your blood sugar.
Painful Diabetic Peripheral Neuropathy Study
Do you have Painful Diabetic Peripheral Neuropathy (PDPN)? You may be eligible to participate in a research study to find out if different treatments have an effect on painful neuropathy due to diabetes. Compensation is provided.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
DREAM Acute Pancreatitis Study
Are you 18-75 years old? Have you recently had an acute pancreatitis attack? You may be able to participate in a study to determine if acute pancreatitis increases your risk for diabetes. This study involves up to 9 visits over 3-5 years, and includes providing blood samples and undergoing tests to detect diabetes. Compensation is provided.
Coping with Type 2 Diabetes
Do you have type 2 diabetes? Do you have a spouse or partner that is willing to participate with you in a research study? You may be eligible to participate in a research study that may improve the health and happiness of both partners. Compensation provided.
Combining Obesity, NAFLD, and Diabetes Management Study through Integrated Treatment Pathways (CONDUIT)
Are you over 18 with presence of a problem closely associated with NAFLD non-alcoholic fatty liver disease: Including: Coronary artery disease and/or stroke, type 2 diabetes mellitus, Obstructive sleep apnea, hypertension (high blood pressure), hyperlipidemia (high cholesterol), obesity (BMI greater than 30 kg/m2 ), gout, and/or polycystic ovary syndrome?
TrialNET Pathway to Prevention 18-45
Do you have a relative who has been diagnosed with type 1 diabetes? Are you aged 18-45? You may be able to take part in a research study to help better understand the development of type 1 diabetes in adults who have a family member with the disease. People found to be at an increased risk for type 1 diabetes may qualify for additional research studies.
TrialNet TOPPLE Type 1 Diabetes Study
Were you diagnosed with type 1 diabetes in the past 48 months? Are you 18-45 years old? You may be able to participate in a research study to test a new therapy that is designed to decrease the immune system attacks on insulin-producing cells. Study participation lasts one year and involves 16 in-person visits. Compensation is provided.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.