About Endocrine System
The endocrine system is made up of different glands which release hormones. Hormones, chemical messengers in the body, play a role in several functions. They regulate digestion, control sexual characteristics and reproduction, initiate growth, increase alertness, relieve stress, and much more. If hormones aren’t produced or processed properly, other organs may not be able to function. For example, diabetes, when the pancreas cannot produce insulin properly, can cause damage to the eyes, kidneys, nervous system, heart, and blood vessels. Other endocrine conditions can affect growth, sexual drive and reproductive abilities, weight regulation, and mood.
The ESSENCE Study
Have you been diagnosed with (by liver biopsy), or are you at high risk of developing (have type 2 diabetes, are obese, and/or have high cholesterol), nonalcoholic steatohepatitis (NASH)? You may be able to participate in a study to evaluate an investigational drug for its ability to treat NASH. This study involves 21 visits and up to 9 phone calls over 5 years. Compensation is provided.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
Referral to Physical Activity Research Study
Are you aged 40-70, don’t regularly exercise, and have been told by a physician that you have one of the following: overweight/obesity, high blood pressure, and/or prediabetes? You may be able to participate in a study to help you increase your activity levels. This study involves completing a computer-based program with tracking tools and goal setting materials. Compensation is provided.
DREAM Acute Pancreatitis Study
Are you 18-75 years old? Have you recently had an acute pancreatitis attack? You may be able to participate in a study to determine if acute pancreatitis increases your risk for diabetes. This study involves up to 9 visits over 3-5 years, and includes providing blood samples and undergoing tests to detect diabetes. Compensation is provided.
GLADIATOR STUDY- A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual β-cell Function (LDX0319)
Are you 18-45 years old and have you been newly diagnosed with Type 1 diabetes (first insulin dose within 100 days)? You may be able to participate in a study to find out if an investigational drug called ladarixin is safe and effective and if it is capable of slowing down the progression of type 1 diabetes. Study participation involves about 12 visits, up to 2 years. Compensation is provided.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Are you a UPMC patient who was newly diagnosed with diabetes or high blood sugar (hyperglycemia) in the past three months? Are you 50-85 years old? You may be able to participate in a research study to help learn more about the relationship between hyperglycemia/diabetes and pancreatic cancer. Study participation involves questionnaires and providing blood samples. Compensation provided.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
TrialNet TOPPLE Type 1 Diabetes Study
Were you diagnosed with type 1 diabetes in the past 48 months? Are you 18-45 years old? You may be able to participate in a research study to test a new therapy that is designed to decrease the immune system attacks on insulin-producing cells. Study participation lasts one year and involves 16 in-person visits. Compensation is provided.
TrialNET Pathway to Prevention 18-45
Do you have a relative who has been diagnosed with type 1 diabetes? Are you aged 18-45? You may be able to take part in a research study to help better understand the development of type 1 diabetes in adults who have a family member with the disease. People found to be at an increased risk for type 1 diabetes may qualify for additional research studies.
Diabetes in the Social Environment (DSE Study)
Are you an African American male with type 2 diabetes? Were you diagnosed 5-15 years ago? If so, you may be able to participate in a research study to better understand how friends and family help you manage your diabetes. Eligible participants are unmarried and not living with a romantic partner, and must have a friend or family member willing to participate. Compensation provided.