About Food, Nutrition, and Metabolism
The choice of what to eat, and how much, can alter the way the entire rest of the body functions. Vitamins, minerals, and other nutrients are needed to create and repair cells, while carbohydrates, fats, and proteins can be converted into energy (a process known as metabolism). An unhealthy diet could impact energy levels, cause digestive issues, or increase the risk for other diseases. Occasionally, foods can trigger a strong reaction from the immune system, as is the case with food allergies or celiac disease; severe reactions can be life threatening, and often these conditions can force people to alter their diet. Eating disorders, such as bulimia or anorexia, cause damage to the entire body by depriving it of vital nutrients.
Personality, Affect, Interactions, and Risk for Suicide (PAIRS) Study
Are you between the ages of 18-35? You may be able to participate in a study that understand how certain types of social interactions influence mood, decision-making, and biological responses that may contribute to risk for suicidal behaviors among young adults.
Neurofeedback for Borderline Personality Disorder Study
Are you 18-55 years old and been diagnosed with borderline personality disorder? If so, you may be able to participate in a research study to find out if an intervention called neurofeedback can improve symptoms in people with borderline personality disorder. Participation involves interviews, questionnaires, and MRI scanning. Compensation provided.
The NN9500-4656 Study
Do you want to address your liver health? Do you have non-alcoholic steatohepatitis (NASH)? You may be able to participate in a study that is evaluating three investigational drugs for their ability to treat NASH.
Alcoholic Hepatitis Network Observational Study - Heavy Drinkers
Do you actively consume alcohol - do you consume at least 20 drinks per week (women) and at least 30 drinks per week (men) and have no known history of liver diseases? Participants will undergo a physical exam, blood draws, provide urine and stool samples, and complete questionnaires.
Familial Pathways Study (FamPath): The Role of Inflammation and Stress in Youth Suicidal Behavior
Are you 18-30 years old and have a diagnosis of mood disorder? You may be eligible to participate in a study to learn more about the role of biological markers of suicidality that may run in families and brain inflammation in suicidal behavior in young adults. Studies suggest increased inflammation is associated with suicidal behavior. Compensation provided.
Immune response to influenza vaccine in middle-aged adults
We are seeking adults 50-70 years old who plan to receive an influenza (flu) vaccine from a UPMC doctor or a pharmacy offering FDA licensed egg-free type flu vaccine. This study will involve 3 study visits with blood draws, each fall for 3 flu seasons (2022-2024). We are especially interested in how people with different body weights respond to the flu vaccine.
The Alcohol Survey Knowledge (ASK) Study
Are you between the ages of 21 and 60 and would you say that you have been a heavy drinker (i.e. 4 or 5 drinks twice/month for a three month period) within the past 2 years? You may be able to participate in a research study that will help to understand how people describe their experience with impaired control over alcohol use.
Bone Adaptations to Physical Training
The primary purpose is to determine the bone density, structure and strength adaptations that result from various exercise programs which differ based on the frequency and intensity of bone loading. Subjects will complete 24 weeks of resistance training or maintain their current activity level without beginning any formal exercise training program and participate in laboratory visits.
MyPaTH Story Booth 2.0
Interested in sharing your story about health, illness, or research? Patients and caregivers are needed to participate in a research study to help learn more about topics that are important to you and that may improve health and health care. Participation involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
MyPaTH Story Booth – COVID-19 Stories
Participants are invited to share how they are maintaining their health during the coronavirus pandemic, or to share what it is like being ill with COVID-19 and/or caring for a loved one who is ill with COVID-19. Participation in this research study involves one 45-minute session that takes place over the phone. Eligible participants must be able to read and understand English.
Pain in the Brain Study for Individuals with Suicidal Thoughts and Non-Suicidal Self-Injury
Have you recently had suicidal thoughts and engaged in non-suicidal self-injury, such as cutting? Are you aged 18-24? You may be able to participate in a research study to help better understand why some people harm themselves on purpose and to learn more about how physical pain and emotional pain may be related in the brain. Compensation provided.
Brain Inflammation in Suicidal Behavior in Young Adults
Are you 18-30 years old and currently receiving mental health treatment? You may be able to participate in a study to learn more about inflammatory markers related to suicidal behavior in young adults. This study involves completing an interview and questionnaires, bloodwork, and an MRI and PET scan of the brain. Compensation is provided.
Benzodiazepine Discontinuation Study
Are you currently receiving opioid maintenance treatment (methadone or buprenorphine)? And do you regularly take benzodiazepines (such as Valium, Klonopin, or Xanax) and are interested in discontinuing benzodiazepine use? You may be able to participate in a research study that will help you to slowly stop taking benzodiazepines by teaching you skills to help with withdrawal.
All of Us Pennsylvania Research Program
You may be able to change the future of medicine. The All of Us PA Research Program is enrolling adults 18 years of age or older. This may be your chance to improve how your children and your children’s children receive medical care.
Hormonal Skin Patch for Women with Anorexia Nervosa
Are you a 19-45 year old woman diagnosed with anorexia nervosa? You may be able to participate in a research study to help find out if a hormonal skin patch can improve bone density in women with anorexia nervosa. Participation involves imaging studies, blood tests, and nutritional analyses. Compensation is provided.
EASY Research Study – Ages 18-24
Are you an 18-24 year old who has recently accessed emergency or crisis services for behavioral health related issues? If so, you may be able to take part in a research study to help better understand how to assess mood, behaviors, and suicide risk in young adults. This study involves four online or phone sessions over about one year. Compensation is provided.